5402-60-8

Basic information

• Product Name: 2,6-Dimethylbenzyl chloride
• Synonyms: 1-CHLOROMETHYL-2,6-DIMETHYLBENZENE;2-CHLOROMETHYL-1,3-DIMETHYL-BENZENE;2,6-DIMETHYLBENZYL CHLORIDE;2-(Chloromethyl)-1,3-dimethylbenzene, 2-(Chloromethyl)-m-xylene;[(2,6-diMethylphenyl)Methyl]chloranuide
• CAS NO: 5402-60-8
• Molecular Formula: C₉H₁₁Cl
• Molecular Weight: 154.64
• Product Categories: Benzene derivatives
• Mol File: 5402-60-8.mol
• Article Data: 10

Chemical Properties

• Melting Point: 33-35°C
• Boiling Point: 70°C 5mm
• Flash Point: 33 °C
• Appearance: /
• Density: 1.033 g/cm³
• Vapor Pressure: 0.132mmHg at 25°C
• Refractive Index: 1.522
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2,6-Dimethylbenzyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dimethylbenzyl chloride(5402-60-8)
• EPA Substance Registry System: 2,6-Dimethylbenzyl chloride(5402-60-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 3261
• HazardClass: IRRITANT, LACHRYMATOR
• Hazardous Substances Data: 5402-60-8(Hazardous Substances Data)

Usage

Description

2,6-Dimethylbenzyl chloride, with the chemical formula C9H11Cl, is a colorless to pale yellow liquid characterized by a strong, pungent odor. It is a versatile chemical intermediate that plays a significant role in the synthesis of various organic compounds, particularly in the production of pharmaceuticals, agrochemicals, and dyes.

Uses

Used in Pharmaceutical Industry:
2,6-Dimethylbenzyl chloride is used as a key intermediate for the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a building block in the development of new drugs, contributing to the advancement of medical treatments.
Used in Agrochemical Industry:
In the agrochemical sector, 2,6-Dimethylbenzyl chloride is utilized as a precursor in the production of insecticides. Its chemical properties make it suitable for creating effective compounds that help protect crops from pests and enhance agricultural productivity.
Used in Dye Industry:
2,6-Dimethylbenzyl chloride is employed as a crucial intermediate in the manufacturing of dyes. Its versatility in chemical reactions enables the creation of a wide range of colorants used in various applications, including textiles, plastics, and printing inks.
Used in Disinfectant Production:
This chemical compound is also used as a building block in the synthesis of disinfectants. Its ability to form stable compounds with biocidal properties makes it valuable in the development of products that help maintain cleanliness and prevent the spread of diseases.
Safety Considerations:
Due to its degree of toxicity, 2,6-Dimethylbenzyl chloride should be handled with caution. It is essential to work in a well-ventilated environment and follow proper safety protocols to minimize health risks associated with its use in various industrial processes.

InChI:InChI=1/C9H11Cl/c1-7-4-3-5-8(2)9(7)6-10/h3-5H,6H2,1-2H3

Upstream product

• 632-46-2 2,6-dimethylbenzoic acid 
• 62285-58-9 2,6-dimethylbenzyl alcohol 
• 608-28-6 2,6-dimethyliodobenzene 
• 50-00-0 formaldehyd 
• 108-38-3 m-xylene 
• 7093-91-6 chloromethyl isocyanate 
• 87-62-7 2,6-dimethylaniline 
• 1123-56-4 2,6-dimethylbenzaldehyde 

Downstream Products

• 19289-31-7 3-<2,6-Dimethyl-benzyloxy>-3-methyl-acrylsaeureethylester 
• 713530-68-8 6-bromo-N-(2,6-dimethylbenzyl)-1,2-dimethyl-1H-benzimidazol-4-amine 
• 938-50-1 2-(2,6-dimethylphenyl)acetic acid 
• 94204-40-7 diethyl 2-(2,6-dimethylphenyl)malonate 
• 105337-15-3 ethyl 2-(2,6-dimethylphenyl)acetate 
• 76574-87-3 6-(2,6-Dimethyl-phenyl)-2-methyl-pyrido[2,3-d]pyrimidin-7-ylamine 
• 76574-64-6 6-(2,6-Dimethyl-phenyl)-pyrido[2,3-d]pyrimidin-7-ylamine 
• 1055039-07-0 Acetic acid 3-{(1S,2S)-1-benzyl-3-[(R)-4-(2,6-dimethyl-benzylcarbamoyl)-thiazolidin-3-yl]-2-hydroxy-3-oxo-propylcarbamoyl}-2-methyl-phenyl ester 
• 226997-95-1 (R)-N-(2,6-dimethylbenzyl)-3-<(2S,3S)-3-amino-2-hydroxy-4-phenylbutanoyl>-1,3-thiazolidine-4-carboxamide 
• 1027226-32-9 4-(2,6-dimethyl-benzylcarbamoyl)-thiazolidine-3-carboxylic acid tert-butyl ester 
• 186538-17-0 (R)-N-(2,6-dimethylbenzyl)-1,3-thiazolidine-4-carboxamide 
• 74788-82-2 (2,6-dimethylphenyl)methanamine 
• 1001096-12-3 C₂₄H₃₀NO₄P 

Relevant articles and documents

PROCESS FOR PREPARING 2,6-DIALKYLPHENYLACETIC ACIDS

The invention relates to a multi-stage process for preparing 2,6-dialkylphenylacetic acids of the general formula (I) by reacting 2,6-dialkylbromobenzenes with (1) magnesium, (2) a formamide, (3) an acid, (4) hydrogenation of the benzaldehyde obtained, (5

BENZODIAZEPINONE COMPOUNDS USEFUL IN THE TREATMENT OF SKIN CONDITIONS

The present invention provides a family of benzodiazepinone compounds and pharmaceutical compositions thereof. The present invention also provides methods of treating certain skin conditions, e.g., atopic dermatitis, rosacea, or psoriasis, by administering a benzodiazepinone and methods of reducing the proliferation of keratinocyte cells by exposing such cells to a benzodiazepinone.

COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS

Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed. Formula (I), wherein n is 1 or 2; m is 0 or 1; q is 0 or 1; t is 0 or 1; R5 is alkyl having from 1 to 3 carbon atoms; R9 is hydrogen, halo, alkyl having from 1 to 3 carbon atoms, or alkoxy having from 1 to 3 carbon atoms; A is phenyl, unsubstituted or substituted by 1 or 2 groups selected from: halo, alkyl having 1 or 2 carbon atoms, perfluoromethyl, alkoxy having 1 or 2 carbon atoms, and perfluoromethoxy; or cycloalkyl having from 3 to 6 ring carbon atoms wherein the cycloalkyl is unsubstituted or one or two ring carbons are independently mono-substituted by methyl or ethyl; or a 5 or 6 membered heteroaromatic ring having 1 or 2 ring heteroatoms selected from N, S and 0 and the heteroaromatic ring is covalently bound to the remainder of the compound of formula I by a ring carbon; and X is -CH2-, Q is -OR1and R1 is methyl or ethyl; or X is -CH2CR12R13- or - CH2CH(NHAc)-wherein each of R12 and R13is independently hydrogen or methyl, Q is OR1 and R1 is hydrogen or alkyl having from 1 to 7 carbon atoms; or X is -CH2CH2- and Q is NR10R1'wherein one of R10 and R11is hydrogen, alkyl having from 1 to 3 carbon atoms or hydroxy, and the other is hydrogen. Alternatively, when R1 is hydrogen, the biologically active agent can be a pharmaceutically acceptable salt of the compound of Formula (I).