2-(hept-2-ynoyl)phenyl acetate

Base Information

• Chemical Name: 2-(hept-2-ynoyl)phenyl acetate
• CAS No.: 1403475-68-2
• Molecular Formula: C₁₅H₁₆O₃
• Molecular Weight: 244.29
• Mol file: 1403475-68-2.mol

Synonyms:2-(hept-2-ynoyl)phenyl acetate

Chemical Property of 2-(hept-2-ynoyl)phenyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-(hept-2-ynoyl)phenyl acetate

There total 3 articles about 2-(hept-2-ynoyl)phenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

hex-1-yne (693-02-7) + O-acetylsalicyloyl chloride (5538-51-2) → 2-(hept-2-ynoyl)phenyl acetate (1403475-68-2)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In tetrahydrofuran; at 20 ℃; for 1h; Schlenk technique; Inert atmosphere;

DOI:10.1039/d0cc01238f

Reference yield: 70.0%

4, 6-dimethoxy-1,3,5-triazinal-2-yl 2-acetoxybenzoate + hex-1-yne (693-02-7) → 2-(hept-2-ynoyl)phenyl acetate (1403475-68-2)

Guidance literature:

4, 6-dimethoxy-1,3,5-triazinal-2-yl 2-acetoxybenzoate; hex-1-yne; With palladium diacetate; In acetonitrile; at 50 ℃; for 10h; Inert atmosphere; Schlenk technique;

With 4-methyl-morpholine; In acetonitrile; for 8h; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.molcata.2016.10.030

Reference yield: 70.0%

4, 6-dimethoxy-1,3,5-triazinal-2-yl 2-acetoxybenzoate + hex-1-yne (693-02-7) → 2-(hept-2-ynoyl)phenyl acetate (1403475-68-2) + 2-hydroxy-4,6-dimethoxy-1,3,5-triazine (1075-59-8)

Guidance literature:

With palladium diacetate; In acetonitrile; at 50 ℃; for 10h; Inert atmosphere;

DOI:10.1021/acs.orglett.5b01466

upstream raw materials:

hex-1-yne

O-acetylsalicyloyl chloride