N-(2-((4-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-yl)amino)ethyl)-4-methoxybenzamide

Base Information

Chemical Name:N-(2-((4-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-yl)amino)ethyl)-4-methoxybenzamide
CAS No.:1261242-30-1
Molecular Formula:C₂₅H₂₁FN₆O₂S
Molecular Weight:488.545
Hs Code.:

Synonyms:N-(2-((4-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-yl)amino)ethyl)-4-methoxybenzamide

Suppliers and Price of N-(2-((4-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-yl)amino)ethyl)-4-methoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-((4-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-yl)amino)ethyl)-4-methoxybenzamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2-((4-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-yl)amino)ethyl)-4-methoxybenzamide

There total 7 articles about N-(2-((4-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-yl)amino)ethyl)-4-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 815595-78-9
6-(4-fluorophenyl)-5-(2-(methylsulfonyl)pyrimidin-4-yl)imidazo[2,1-b]thiazole

: 65136-87-0
N?(2?aminoethyl)?4?methoxybenzamide

: 1261242-30-1
N-(2-((4-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-yl)amino)ethyl)-4-methoxybenzamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; at 80 ℃; for 8h;
DOI:10.1007/s00044-016-1529-7

Reference yield:

: 1261242-15-2
C₁₈H₂₀N₂O₄

: 1261242-30-1
N-(2-((4-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-yl)amino)ethyl)-4-methoxybenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: palladium on activated charcoal; hydrogen / methanol / 1 h / 20 °C

2: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 8 h / 80 °C

With palladium on activated charcoal; hydrogen; N-ethyl-N,N-diisopropylamine; In methanol; dimethyl sulfoxide;
DOI:10.5012/bkcs.2010.31.10.2854

Reference yield:

: 815595-77-8
6-(4-fluorophenyl)-5-(2-(methylthio)pyrimidin-4-yl)imidazo[2,1-b]thiazole

: 1261242-30-1
N-(2-((4-(6-(4-fluorophenyl)imidazo[2,1-b]thiazol-5-yl)pyrimidin-2-yl)amino)ethyl)-4-methoxybenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: oxone / methanol; water / 16 h / 20 °C

2: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 8 h / 80 °C

With oxone; N-ethyl-N,N-diisopropylamine; In methanol; water; dimethyl sulfoxide;
DOI:10.5012/bkcs.2010.31.10.2854