m-(p-Toluidino)phenol

Base Information

Chemical Name:m-(p-Toluidino)phenol
CAS No.:61537-49-3
Molecular Formula:C13H13 N O
Molecular Weight:199.252
Hs Code.:2922299090
European Community (EC) Number:262-832-2
UNII:Z87QB9R59T
DSSTox Substance ID:DTXSID00210526
Nikkaji Number:J29.873E
Wikidata:Q72481169
Mol file:61537-49-3.mol

Synonyms:61537-49-3;3-(p-Tolylamino)phenol;m-(p-Toluidino)phenol;N-(3-HYDROXYPHENYL)-4-TOLUIDINE;3-(4-methylanilino)phenol;3-[(4-methylphenyl)amino]phenol;3-Hydroxy-4'-methyldiphenylamine;3-p-Tolylamino-phenol;Phenol, 3-[(4-methylphenyl)amino]-;EINECS 262-832-2;Z87QB9R59T;3-(p-toluidino)phenol;3-((4-METHYLPHENYL)AMINO)PHENOL;PHENOL, 3-((4-METHYLPHENYL)AMINO)-;3-[(4-Methylphenyl)amino] phenol;Phentolamine Mesylate EP Impurity C;m-Oxyphenyl-p-tolylamin;UNII-Z87QB9R59T;3-(4-Methylphenylamino)phenol;SCHEMBL3230812;DTXSID00210526;3-Hydroxy-4'-methyl diphenylamine;BBL034803;MFCD01076315;STL426724;AKOS006272581;AC-20395;AS-17509;A8531;CS-0172144;FT-0725779;W-105139;PHENTOLAMINE MESILATE IMPURITY C [EP IMPURITY];3-HYDROXY-4'-METHYLDIPHENYLAMINE

Suppliers and Price of m-(p-Toluidino)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-[(4-Methylphenyl)amino]phenol
1g
$ 760.00

Crysdot
3-(p-Tolylamino)phenol 97%
5g
$ 470.00

American Custom Chemicals Corporation
N-(3-HYDROXYPHENYL)-4-TOLUIDINE 95.00%
5G
$ 999.31

Alichem
3-(p-Tolylamino)phenol
5g
$ 1284.72

Alichem
3-(p-Tolylamino)phenol
250mg
$ 163.62

AK Scientific
3-(p-Toluidino)phenol
5g
$ 343.00

Total 50 raw suppliers

Chemical Property of m-(p-Toluidino)phenol

Chemical Property:

Vapor Pressure:1.2E-05mmHg at 25°C
Melting Point:82 °C
Boiling Point:358.9 °C at 760 mmHg
PKA:9.88±0.10(Predicted)
Flash Point:151 °C
PSA：32.26000
Density:1.17 g/cm³
LogP:3.51720
Storage Temp.:2-8°C
XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:199.099714038
Heavy Atom Count:15
Complexity:187

Purity/Quality:

99%, ^*data from raw suppliers

3-[(4-Methylphenyl)amino]phenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)NC2=CC(=CC=C2)O
Uses 3-[(4-Methylphenyl)amino]phenol, is the reagent that can be used in the preparation of Phentolamine Hydrochloride (P302550), an adrenergic blocking agent, and an antihypertensive

Technology Process of m-(p-Toluidino)phenol

There total 15 articles about m-(p-Toluidino)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 106-38-7
para-bromotoluene

: 591-27-5
m-Hydroxyaniline

: 61537-49-3
4-methyl-3'-hydroxydiphenylamine

Guidance literature:: With 2'-dicyclohexylphosphanyl-6-hydroxy-biphenyl-3-sulfonic acid; palladium diacetate; sodium t-butanolate; In diethylene glycol dimethyl ether; at 120 ℃; for 15h; Inert atmosphere;
DOI:10.1016/j.bmc.2018.07.028

Reference yield: 92.0%

: 61537-49-3
4-methyl-3'-hydroxydiphenylamine

Guidance literature:: With nickel(II) bromide trihydrate; N,N-dimethyl-cyclohexanamine; C₇₀H₇₅BN₂; In 1,2-dimethoxyethane; N,N-dimethyl-formamide; at 50 ℃; for 12h; Inert atmosphere; Irradiation;

Reference yield: 85.0%

: 36646-74-9
3-(p-tolylamino)cyclohex-2-en-1-one

: 61537-49-3
4-methyl-3'-hydroxydiphenylamine

Guidance literature:: With methanol; palladium 10% on activated carbon; at 210 ℃; for 48h; Time; Inert atmosphere;
DOI:10.3390/molecules180910334