3-deoxy-5,6:7,8-di-O-isopropylidene-D-gluco-oct-2-ulosonic acid 2,6-di-t-butyl-4-methoxyphenyl ester

Base Information

• Chemical Name: 3-deoxy-5,6:7,8-di-O-isopropylidene-D-gluco-oct-2-ulosonic acid 2,6-di-t-butyl-4-methoxyphenyl ester
• CAS No.: 1427025-40-8
• Molecular Formula: C₂₉H₄₄O₉
• Molecular Weight: 536.663
• Mol file: 1427025-40-8.mol

Synonyms:3-deoxy-5,6:7,8-di-O-isopropylidene-D-gluco-oct-2-ulosonic acid 2,6-di-t-butyl-4-methoxyphenyl ester

Chemical Property of 3-deoxy-5,6:7,8-di-O-isopropylidene-D-gluco-oct-2-ulosonic acid 2,6-di-t-butyl-4-methoxyphenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-deoxy-5,6:7,8-di-O-isopropylidene-D-gluco-oct-2-ulosonic acid 2,6-di-t-butyl-4-methoxyphenyl ester

There total 1 articles about 3-deoxy-5,6:7,8-di-O-isopropylidene-D-gluco-oct-2-ulosonic acid 2,6-di-t-butyl-4-methoxyphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

2,6-di-tert-butyl-4-methoxyphenyl pyruvate (145656-72-0) + 2,2:4,5-di-O-isopropylidene-D-arabinose (13039-93-5) → 3-deoxy-5,6:7,8-di-O-isopropylidene-D-gluco-oct-2-ulosonic acid 2,6-di-t-butyl-4-methoxyphenyl ester (1427025-40-8) + 3-deoxy-5,6:7,8-di-O-isopropylidene-D-manno-oct-2-ulosonic acid 2,6-di-t-butyl-4-methoxyphenyl ester (1427025-41-9)

Guidance literature:

With C₄₅H₄₈N₂O₃Zn₂; In tetrahydrofuran; at -25 ℃; for 96h; Reagent/catalyst; diastereoselective reaction; Inert atmosphere;

DOI:10.1002/adsc.201500169

Reference yield: 98.0%

3-deoxy-5,6:7,8-di-O-isopropylidene-D-gluco-oct-2-ulosonic acid 2,6-di-t-butyl-4-methoxyphenyl ester (1427025-40-8) → 3-deoxy-D-gluco-oct-2-ulosonic acid 2,6-di-tert-butyl-4-methoxyphenyl ester

Guidance literature:

With DOWEX₅₀ WX 4; In methanol; at 20 ℃; for 24h;

DOI:10.1002/ejoc.201600784

Reference yield: 80.0%

3-deoxy-5,6:7,8-di-O-isopropylidene-D-gluco-oct-2-ulosonic acid 2,6-di-t-butyl-4-methoxyphenyl ester (1427025-40-8) → C23H36O9

Guidance literature:

With hydrogenchloride; In acetonitrile; for 12h;

DOI:10.1002/adsc.201200914

upstream raw materials:

2,6-di-tert-butyl-4-methoxyphenyl pyruvate

2,2:4,5-di-O-isopropylidene-D-arabinose