Chemical Property of Esculin
Chemical Property:
- Appearance/Colour:White to nearly white
- Vapor Pressure:1.97E-20mmHg at 25°C
- Melting Point:203 °C
- Refractive Index:-79 ° (C=2.4, 50% Dioxane)
- Boiling Point:697.7 °C at 760 mmHg
- PKA:7.00±0.20(Predicted)
- Flash Point:262.8 °C
- PSA：149.82000
- Density:1.679 g/cm3
- LogP:-1.32270
- Storage Temp.:Store at RT.
- Solubility.:methanol: 50 mg/mL hot, clear to very faintly turbid, yello
- Water Solubility.:MODERATELY SOLUBLE
- XLogP3:-0.6
- Hydrogen Bond Donor Count:5
- Hydrogen Bond Acceptor Count:9
- Rotatable Bond Count:3
- Exact Mass:340.07943208
- Heavy Atom Count:24
- Complexity:495
- Purity/Quality:
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99%HPLC *data from raw suppliers
Esculin *data from reagent suppliers
Safty Information:
- Pictogram(s):
F, 
C, 
Xi
- Hazard Codes:F,C,Xi
- Statements:
11-20/21/22-34-68/20/21/22-36/37/38
- Safety Statements:
26-36/37/39-45-24/25-36/37-16
- MSDS Files:
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Useful:
- Canonical SMILES:C1=CC(=O)OC2=CC(=C(C=C21)OC3C(C(C(C(O3)CO)O)O)O)O
- Isomeric SMILES:C1=CC(=O)OC2=CC(=C(C=C21)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O
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Description
Aesculin (also Esculin) is a glucoside compound, which occurs naturally in unprocessed seeds, leaves, bark, and flowers of horse chestnut. Aesculin is used for the identification of bacteria, for the treatment of hemorrhoids and venous peripheral diseases. In cosmetics, aesculin was found to be effective in the treatment of aging skin. Owing to its ultraviolet absorbing activity, aesculin is employed in tanning preparations. Aesculin can be also used as a substrate for the detection of ?-gluocosidase activity in polyacrylamide gels.
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Uses
esculin is used as a skin protectant in ointments and creams. This is a glucoside compound originally obtained from the leaves and bark of the horse chestnut tree. esculoside is utilized in formulations for the treatment of cellulite. es culoside is apparently beneficial for impaired microcirculation. Esculin hydrate has been used as a component of sporulation-inducing esculin agar. It has also been used for esculin uptake assay.
