N¹,N¹-diisopropyl-N²-(4-methylbenzenesulfonyl)-2-(4-methylphenyl)acetamidine

Base Information

• Chemical Name: N¹,N¹-diisopropyl-N²-(4-methylbenzenesulfonyl)-2-(4-methylphenyl)acetamidine
• CAS No.: 847740-51-6
• Molecular Formula: C₂₂H₃₀N₂O₂S
• Molecular Weight: 386.558
• Mol file: 847740-51-6.mol

Synonyms:N¹,N¹-diisopropyl-N²-(4-methylbenzenesulfonyl)-2-(4-methylphenyl)acetamidine

Chemical Property of N¹,N¹-diisopropyl-N²-(4-methylbenzenesulfonyl)-2-(4-methylphenyl)acetamidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N¹,N¹-diisopropyl-N²-(4-methylbenzenesulfonyl)-2-(4-methylphenyl)acetamidine

There total 4 articles about N¹,N¹-diisopropyl-N²-(4-methylbenzenesulfonyl)-2-(4-methylphenyl)acetamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-toluenesulfonyl azide (941-55-9) + diisopropylamine (108-18-9) + 4-n-methylphenylacetylene (766-97-2) → N1,N1-diisopropyl-N2-(4-methylbenzenesulfonyl)-2-(4-methylphenyl)acetamidine (847740-51-6)

Guidance literature:

With Cu₂I₂(benzene-1,3,5-triyl triisonicotinate); In acetonitrile; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ic4012229

Reference yield: 85.0%

1-(4-methylbenzenesulfonyl)-4-(4-methylphenyl)-1,2,3-triazole + diisopropylamine (108-18-9) → N1,N1-diisopropyl-N2-(4-methylbenzenesulfonyl)-2-(4-methylphenyl)acetamidine (847740-51-6)

Guidance literature:

With silver carbonate; In toluene; at 80 ℃; for 12h; Inert atmosphere;

DOI:10.1055/s-0036-1588103

Reference yield: 83.0%

→ N1,N1-diisopropyl-N2-(4-methylbenzenesulfonyl)-2-(4-methylphenyl)acetamidine (847740-51-6)

Guidance literature:

With heterogeneous copper catalyst; In acetonitrile; at 25 ℃; for 3h; Inert atmosphere;

upstream raw materials:

p-toluenesulfonyl chloride

4-toluenesulfonyl azide

diisopropylamine

4-n-methylphenylacetylene