2-[2,6-dimethyl-4-({[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino}methyl)phenoxy]-2-methylpropanoate

Base Information

• Chemical Name: 2-[2,6-dimethyl-4-({[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino}methyl)phenoxy]-2-methylpropanoate
• CAS No.: 866640-93-9
• Molecular Formula: C₂₆H₃₂N₂O₄
• Molecular Weight: 436.551

Synonyms:2-[2,6-dimethyl-4-({[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino}methyl)phenoxy]-2-methylpropanoate

Chemical Property of 2-[2,6-dimethyl-4-({[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino}methyl)phenoxy]-2-methylpropanoate

Chemical Property:

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Technology Process of 2-[2,6-dimethyl-4-({[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino}methyl)phenoxy]-2-methylpropanoate

There total 1 articles about 2-[2,6-dimethyl-4-({[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino}methyl)phenoxy]-2-methylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-[2,6-dimethyl-4-({[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino}methyl)phenoxy]-2-methylpropanoate (866640-93-9)

Guidance literature:

Reference yield: 91.0%

2-[2,6-dimethyl-4-({[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino}methyl)phenoxy]-2-methylpropanoate (866640-93-9) + Glyoxilic acid (298-12-4) → 2N-{4-[(1-ethoxy-2-methyl-1-oxopropan-2-yl)oxy]-3,5-dimethylbenzyl}-N-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)-methyl]glycine (866718-44-7)

Guidance literature:

With sodium tris(acetoxy)borohydride; In methanol; at 20 ℃;

DOI:10.1248/cpb.c15-00221

Reference yield: 71.0%

2-[2,6-dimethyl-4-({[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino}methyl)phenoxy]-2-methylpropanoate (866640-93-9) + N-(t-butoxycarbonyl)glycinal (89711-08-0) → ethyl 2-{4-[({2-[(tert-butoxycarbonyl)amino]ethyl}[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino)methyl]-2,6-dimethylphenoxy}-2-methylpropanoate

Guidance literature:

With sodium tris(acetoxy)borohydride; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1248/cpb.c15-00221

Downstream raw materials:

C₃₁H₃₈N₄O₄

2-[2,6-dimethyl-4-({[(1-methyl-1H-imidazol-2-yl) methyl]-[(5-methyl-2-phenyl-1,3-oxazol-4-yl) methyl] amino}methyl)-phenoxy]-2-methylpropanoic acid

2-[4-({[2-(cyclopropylamino)-2-oxoethyl][(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amino}methyl)-2,6-dimethylphenoxy]-2-methylpropanoic acid

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