6-(2-hydroxyethyl)-1,3-dimethyl-5-phenyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione

Base Information

Chemical Name:6-(2-hydroxyethyl)-1,3-dimethyl-5-phenyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione
CAS No.:848217-05-0
Molecular Formula:C₁₆H₁₇N₃O₃
Molecular Weight:299.329
Hs Code.:
DSSTox Substance ID:DTXSID201127724

Synonyms:6-(2-hydroxyethyl)-1,3-dimethyl-5-phenyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione;848217-05-0;SCHEMBL15796480;DTXSID201127724;STL345542;AKOS022111250

Suppliers and Price of 6-(2-hydroxyethyl)-1,3-dimethyl-5-phenyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-(2-hydroxyethyl)-1,3-dimethyl-5-phenyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione

Chemical Property:

XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:299.12699141
Heavy Atom Count:22
Complexity:450

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C2=CN(C(=C2C(=O)N(C1=O)C)C3=CC=CC=C3)CCO

Technology Process of 6-(2-hydroxyethyl)-1,3-dimethyl-5-phenyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione

There total 3 articles about 6-(2-hydroxyethyl)-1,3-dimethyl-5-phenyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 141-43-5
ethanolamine

: 443667-38-7
5-benzoyl-6-(bromomethyl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

: 848217-05-0
6-(2-hydroxyethyl)-1,3-dimethyl-5-phenyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione

Guidance literature:: With triethylamine; In ethanol; at 100 ℃; for 1.33h; Microwave irradiation;

Reference yield:

: 13509-52-9
1,3,6-trimethyluracil

: 848217-05-0
6-(2-hydroxyethyl)-1,3-dimethyl-5-phenyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione

Guidance literature:: Multi-step reaction with 3 steps

1: zinc(II) chloride / chlorobenzene / 16 h / 110 °C / Inert atmosphere

2: bromine / chloroform / 2.5 h / 55 °C / Inert atmosphere

3: triethylamine / ethanol / 1.33 h / 100 °C / Microwave irradiation

With bromine; triethylamine; zinc(II) chloride; In ethanol; chloroform; chlorobenzene;

Reference yield:

: 444058-30-4
5-benzoyl-1,3,6-trimethylpyrimidine-2,4(1H,3H)-dione

: 848217-05-0
6-(2-hydroxyethyl)-1,3-dimethyl-5-phenyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione

Guidance literature:: Multi-step reaction with 2 steps

1: bromine / chloroform / 2.5 h / 55 °C / Inert atmosphere

2: triethylamine / ethanol / 1.33 h / 100 °C / Microwave irradiation

With bromine; triethylamine; In ethanol; chloroform;