Technology Process of methyl 2,3,6-trideoxy-6-iodo-4-O-benzyl-4-C-methyl-α-D-erythro-hex-2-enopyranoside
There total 4 articles about methyl 2,3,6-trideoxy-6-iodo-4-O-benzyl-4-C-methyl-α-D-erythro-hex-2-enopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetra-(n-butyl)ammonium iodide; sodium hydride;
In
tetrahydrofuran;
at 20 ℃;
for 10h;
DOI:10.1016/S0040-4020(00)01117-0
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 72 percent / methyltriphenoxyphosphonium iodide / dimethylformamide / 1 h / 20 °C
2: 80 percent / diethyl ether / 7 h / 0 - 20 °C
3: 77 percent / sodium hydride; tetrabutylammonium iodide / tetrahydrofuran / 10 h / 20 °C
With
methyltriphenoxyphosphonium iodide; tetra-(n-butyl)ammonium iodide; sodium hydride;
In
tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide;
2: Grignard reaction;
DOI:10.1016/S0040-4020(00)01117-0
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 55 percent / manganese dioxide / CH2Cl2 / 2 h / 20 °C
2: 72 percent / methyltriphenoxyphosphonium iodide / dimethylformamide / 1 h / 20 °C
3: 80 percent / diethyl ether / 7 h / 0 - 20 °C
4: 77 percent / sodium hydride; tetrabutylammonium iodide / tetrahydrofuran / 10 h / 20 °C
With
manganese(IV) oxide; methyltriphenoxyphosphonium iodide; tetra-(n-butyl)ammonium iodide; sodium hydride;
In
tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
3: Grignard reaction;
DOI:10.1016/S0040-4020(00)01117-0
