Chemical Property of 5-Nitro-2-furaldehyde
Chemical Property:
- Appearance/Colour:Yellow to brown crystalline low melting solid
- Vapor Pressure:0.0196mmHg at 25°C
- Melting Point:37-39 °C(lit.)
- Refractive Index:n20/D 1.59(lit.)
- Boiling Point:252.2 °C at 760 mmHg
- Flash Point:118.6 °C
- PSA：76.03000
- Density:1.473 g/cm3
- LogP:1.52350
- Storage Temp.:Flammables area
- Sensitive.:Air & Light Sensitive
- Water Solubility.:sparingly soluble
- XLogP3:1
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:1
- Exact Mass:141.00620758
- Heavy Atom Count:10
- Complexity:152
- Purity/Quality:
-
98% *data from raw suppliers
5-Nitro-2-furaldehyde *data from reagent suppliers
Safty Information:
- Pictogram(s):
F, 
Xn
- Hazard Codes:F,Xi,Xn
- Statements:
11-68-10
- Safety Statements:
16-36/37
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1=C(OC(=C1)[N+](=O)[O-])C=O
-
Description
Nitrofuran carboxaldehyde (NFC) is used to synthesize
many drugs and chemicals such as nifuraldezone, puraguanidine,
nifuratrone, furmethoxadone, etc. Furfural the
main structure of NFC was determined many years ago to be
a byproduct of formic acid synthesis. Furfural is produced
from agricultural byproducts such as sugarcane bagasse and
corncobs.
-
Uses
NFC and its derivatives have antibacterial and antifungal
activities. They destroy both gram-positive and gram-negative
organisms such as Staphylococcus aureus, Salmonella schotmuelleri,
Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and
Streptococcus pyogenes. They may be used as antibacterial agents
in a prophylactic manner, for example, in cleaning and disinfecting
products. 5-Nitrofurfural also has antitrichomonal
and antifungal activities. 5-Nitro-2-furaldehyde was used in the synthesis of a series of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives. . It was also used in the synthesis of modified mesoporous silica (MCM-41). 5-Nitrofurfural can be commonly used as pharmaceutical intermediates.
