2-(6-tert-butylpyridin-3-yl)-2-methyl-N-((1R)-1-{3-methyl-4-[(methylsulfonyl)amino]phenyl}ethyl)cyclopropanecarboxamide

Base Information

Chemical Name:2-(6-tert-butylpyridin-3-yl)-2-methyl-N-((1R)-1-{3-methyl-4-[(methylsulfonyl)amino]phenyl}ethyl)cyclopropanecarboxamide
CAS No.:910485-39-1
Molecular Formula:C₂₄H₃₃N₃O₃S
Molecular Weight:443.61
Hs Code.:

Synonyms:2-(6-tert-butylpyridin-3-yl)-2-methyl-N-((1R)-1-{3-methyl-4-[(methylsulfonyl)amino]phenyl}ethyl)cyclopropanecarboxamide

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Chemical Property of 2-(6-tert-butylpyridin-3-yl)-2-methyl-N-((1R)-1-{3-methyl-4-[(methylsulfonyl)amino]phenyl}ethyl)cyclopropanecarboxamide

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Technology Process of 2-(6-tert-butylpyridin-3-yl)-2-methyl-N-((1R)-1-{3-methyl-4-[(methylsulfonyl)amino]phenyl}ethyl)cyclopropanecarboxamide

There total 1 articles about 2-(6-tert-butylpyridin-3-yl)-2-methyl-N-((1R)-1-{3-methyl-4-[(methylsulfonyl)amino]phenyl}ethyl)cyclopropanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 886842-78-0
N-{4-[(1R)-1-aminoethyl]-2-methylphenyl}methanesulfonamide hydrochloride

: 910486-38-3
2-(6-tert-butylpyridin-3-yl)-2-methylcyclopropanecarboxylic acid

: 910485-39-1
2-(6-tert-butylpyridin-3-yl)-2-methyl-N-((1R)-1-{3-methyl-4-[(methylsulfonyl)amino]phenyl}ethyl)cyclopropanecarboxamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 16h; Product distribution / selectivity;

Reference yield: 100.0%

: 910485-39-1
2-(6-tert-butylpyridin-3-yl)-2-methyl-N-((1R)-1-{3-methyl-4-[(methylsulfonyl)amino]phenyl}ethyl)cyclopropanecarboxamide

: 2-(6-tert-butylpyridin-3-yl)-2-methyl-N-((1R)-1-{3-methyl-4-[(methylsulfonyl)amino]phenyl}ethyl)cyclopropanecarboxamide monohydrochloride

Guidance literature:: With hydrogenchloride; In methanol; at 20 ℃; for 0.5h;

Reference yield:

: N-{4-[(1R)-1-aminoethyl]-2-fluorophenyl}methanesulfonamide hydrochloride

: 910485-39-1
2-(6-tert-butylpyridin-3-yl)-2-methyl-N-((1R)-1-{3-methyl-4-[(methylsulfonyl)amino]phenyl}ethyl)cyclopropanecarboxamide

: 2-[6-tert-butylpyridin-3-yl]-N-((1R)-1-{3-fluoro-4-[(methylsulfonyl)amino]phenyl}ethyl)cyclopropanecarboxamide

: 2-[6-tert-butylpyridin-3-yl]-N-((1R)-1-{3-fluoro-4-[(methylsulfonyl)amino]phenyl}ethyl)cyclopropanecarboxamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide;