C₁₆⁽¹³⁾C₂H₂₆O

Base Information

• Chemical Name: C₁₆⁽¹³⁾C₂H₂₆O
• CAS No.: 347367-55-9
• Molecular Formula: C₁₈H₂₆O
• Molecular Weight: 260.382
• Mol file: 347367-55-9.mol

Synonyms:C₁₆⁽¹³⁾C₂H₂₆O

Chemical Property of C₁₆⁽¹³⁾C₂H₂₆O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆⁽¹³⁾C₂H₂₆O

There total 4 articles about C₁₆⁽¹³⁾C₂H₂₆O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

acetone (67-64-1) + [10,11-13C2]-(2E,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-enyl)penta-2,4-dienal (100187-26-6) → C16(13)C2H26O (347367-55-9)

Guidance literature:

acetone; [10,11-13C₂]-(2E,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-enyl)penta-2,4-dienal; With sodium hydroxide; for 6h;

With silica gel; In hexane; ethyl acetate;

DOI:10.1002/jlcr.464

Reference yield:

(E)-β-ionone (79-77-6,14901-07-6) → C16(13)C2H26O (347367-55-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 99 percent / NaH / diethyl ether

2.1: 99 percent / LiAlH₄ / diethyl ether

3.1: 92 percent / MnO₂ / hexane

4.1: aq. NaOH / 6 h

4.2: 90 percent / SiO₂ / ethyl acetate; hexane

With manganese(IV) oxide; sodium hydroxide; lithium aluminium tetrahydride; sodium hydride; In diethyl ether; hexane; 1.1: Wittig-Horner reaction;

DOI:10.1002/jlcr.464

Reference yield:

C13(13)C2H24O (347367-54-8) → C16(13)C2H26O (347367-55-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 92 percent / MnO₂ / hexane

2.1: aq. NaOH / 6 h

2.2: 90 percent / SiO₂ / ethyl acetate; hexane

With manganese(IV) oxide; sodium hydroxide; In hexane;

DOI:10.1002/jlcr.464

upstream raw materials:

acetone

[10,11-13C₂]-(2E,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-enyl)penta-2,4-dienal

(E)-β-ionone

C₁₃⁽¹³⁾C₂H₂₄O

Downstream raw materials:

10,11,14,15-¹³C₄-retinol

10,11,14,15-¹³C₄-retinoic acid ethyl ester

Refernces