Methyl 2-(trifluoromethyl)cinnamate

Base Information

Chemical Name:Methyl 2-(trifluoromethyl)cinnamate
CAS No.:157518-53-1
Molecular Formula:C₁₁H₉F₃O₂
Molecular Weight:230.186
Hs Code.:
DSSTox Substance ID:DTXSID001155987

Synonyms:METHYL 2-(TRIFLUOROMETHYL)CINNAMATE;157518-53-1;(E)-methyl 3-(2-(trifluoromethyl)phenyl)acrylate;SCHEMBL6818320;DTXSID001155987;MFCD04973007;AKOS017552975;BS-47851;METHYL2-(TRIFLUOROMETHYL)CINNAMATE;F71392;TRANS-METHYL 2-(TRIFLUOROMETHYL)CINNAMATE;methyl (2E)-3-[2-(trifluoromethyl)phenyl]prop-2-enoate;2-Propenoic acid, 3-[2-(trifluoromethyl)phenyl]-, methyl ester, (2E)-

Suppliers and Price of Methyl 2-(trifluoromethyl)cinnamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methyl 2-(trifluoromethyl)cinnamate

Chemical Property:

Boiling Point:254.9±35.0 °C(Predicted)
Density:1.251±0.06 g/cm3(Predicted)
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:230.05546401
Heavy Atom Count:16
Complexity:271

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C=CC1=CC=CC=C1C(F)(F)F
Isomeric SMILES:COC(=O)/C=C/C1=CC=CC=C1C(F)(F)F

Technology Process of Methyl 2-(trifluoromethyl)cinnamate

There total 10 articles about Methyl 2-(trifluoromethyl)cinnamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 88-17-5
2-(trifluoromethyl)benzenamine

: 157518-53-1
methyl (E)-3-<2-(trifluoromethyl)phenyl>propenoate

Guidance literature:: With palladium diacetate; toluene-4-sulfonic acid; In methanol; at 60 ℃; for 1.5h; Inert atmosphere;
DOI:10.1021/acs.joc.8b01910

Reference yield: 82.0%

: 444-29-1
2-iodo(trifluoromethyl)benzene

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 157518-53-1
methyl (E)-3-<2-(trifluoromethyl)phenyl>propenoate

Guidance literature:: With triethylamine; poly{bis[(N-iPr-acrylamide)5-co-((4-vinylphenyl)PPh₂)]PdCl₂}; In toluene; at 100 ℃; for 60h;
DOI:10.1016/j.tet.2004.02.068