Technology Process of 1-(3-Benzenesulfonyl-1,5,5-trimethyl-cyclopent-2-enyl)-ethanone
There total 5 articles about 1-(3-Benzenesulfonyl-1,5,5-trimethyl-cyclopent-2-enyl)-ethanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 96 percent / n-butyllithium / tetrahydrofuran; hexamethylphosphoric acid triamide / -70 °C
2: 50 percent / 80percent aq. sulfuric acid / 0.5 h / 15 °C
3: 1.) N-bromosuccinimide, 2.) lithium chloride, calcium carbonate / 1.) carbon tetrachloride, irradiation, 10 min, 2.) DMF, 110 deg C, 1 h
4: 5 percent Spectr. / sodium hydride / dimethylformamide
With
N-Bromosuccinimide; n-butyllithium; sulfuric acid; sodium hydride; calcium carbonate; lithium chloride;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; N,N-dimethyl-formamide;
DOI:10.1021/ja00525a023
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 50 percent / 80percent aq. sulfuric acid / 0.5 h / 15 °C
2: 1.) N-bromosuccinimide, 2.) lithium chloride, calcium carbonate / 1.) carbon tetrachloride, irradiation, 10 min, 2.) DMF, 110 deg C, 1 h
3: 5 percent Spectr. / sodium hydride / dimethylformamide
With
N-Bromosuccinimide; sulfuric acid; sodium hydride; calcium carbonate; lithium chloride;
In
N,N-dimethyl-formamide;
DOI:10.1021/ja00525a023
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) N-bromosuccinimide, 2.) lithium chloride, calcium carbonate / 1.) carbon tetrachloride, irradiation, 10 min, 2.) DMF, 110 deg C, 1 h
2: 5 percent Spectr. / sodium hydride / dimethylformamide
With
N-Bromosuccinimide; sodium hydride; calcium carbonate; lithium chloride;
In
N,N-dimethyl-formamide;
DOI:10.1021/ja00525a023
