1-(2-benzhydryloxyethyl)piperidine

Base Information

• Chemical Name: 1-(2-benzhydryloxyethyl)piperidine
• CAS No.: 4960-10-5
• Molecular Formula: C20H25NO
• Molecular Weight: 295.425
• Mol file: 4960-10-5.mol

Synonyms:1-Piperidino-2-benzhydryloxy-ethan;1-<2-Diphenylmethoxy-ethyl>-piperidin;Perastine;1-(2-Benzhydryloxy-aethyl)-piperidin;<2-Piperidino-ethyl>-diphenylmethyl-ether;1-(2-benzhydryloxy-ethyl)-piperidine;Perastine [INN];

Chemical Property of 1-(2-benzhydryloxyethyl)piperidine

Chemical Property:

• Vapor Pressure: 1.83E-06mmHg at 25°C
• Boiling Point: 395.5°C at 760 mmHg
• Flash Point: 116.4°C
• PSA: 12.47000
• Density: 1.045g/cm³
• LogP: 4.21640

Purity/Quality:

99% ^*data from raw suppliers

PERASTINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2-benzhydryloxyethyl)piperidine

There total 6 articles about 1-(2-benzhydryloxyethyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(piperidin-4-yl)ethyl chloride (1932-03-2) → 1-(2-benzhydryloxy-ethyl)-piperidine (4960-10-5)

Guidance literature:

With xylene;

Reference yield:

1,1-Diphenylmethanol (91-01-0) → 1-(2-benzhydryloxy-ethyl)-piperidine (4960-10-5)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄; benzene

2: sodium acetate; xylene

With sulfuric acid; sodium acetate; xylene; benzene;

Reference yield:

piperidine (110-89-4) + 1,1'-[(2-chloroethoxy)methylene]bis-benzene (32669-06-0) → 1-(2-benzhydryloxy-ethyl)-piperidine (4960-10-5)

Guidance literature:

With sodium acetate; xylene;

upstream raw materials:

piperidine

1,1'-[(2-chloroethoxy)methylene]bis-benzene

1-piperidinoethanol

Bromodiphenylmethane

Downstream raw materials:

1-ethoxycarbonylmethyl-1-(2-benzhydryloxy-ethyl)-piperidinium; bromide

1-(2-benzhydryloxy-ethyl)-1-methyl-piperidinium; iodide

1-piperidinoethanol

benzhydryl ether