3-((2R,4S,5R,6S)-4,5-dimethoxy-2,6-dimethylnon-7-yn-1-yl)-5-methoxyaniline

Base Information

Chemical Name:3-((2R,4S,5R,6S)-4,5-dimethoxy-2,6-dimethylnon-7-yn-1-yl)-5-methoxyaniline
CAS No.:1332626-22-8
Molecular Formula:C₂₀H₃₁NO₃
Molecular Weight:333.471
Hs Code.:

Synonyms:3-((2R,4S,5R,6S)-4,5-dimethoxy-2,6-dimethylnon-7-yn-1-yl)-5-methoxyaniline

Suppliers and Price of 3-((2R,4S,5R,6S)-4,5-dimethoxy-2,6-dimethylnon-7-yn-1-yl)-5-methoxyaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-((2R,4S,5R,6S)-4,5-dimethoxy-2,6-dimethylnon-7-yn-1-yl)-5-methoxyaniline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-((2R,4S,5R,6S)-4,5-dimethoxy-2,6-dimethylnon-7-yn-1-yl)-5-methoxyaniline

There total 6 articles about 3-((2R,4S,5R,6S)-4,5-dimethoxy-2,6-dimethylnon-7-yn-1-yl)-5-methoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1332626-35-3
N,N-diallyl-3-((2R,4S,5R,6S)-4,5-dimethoxy-2,6-dimethylnon-7-yn-1-yl)-5-methoxyaniline

: 1332626-22-8
3-((2R,4S,5R,6S)-4,5-dimethoxy-2,6-dimethylnon-7-yn-1-yl)-5-methoxyaniline

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; 1,3-dimethylbarbituric acid; In dichloromethane; at 40 ℃; for 3h; Inert atmosphere;
DOI:10.1021/ol2019828

Reference yield:

: 1332626-17-1
N,N-diallyl-3-bromo-5-methoxyaniline

: 1332626-22-8
3-((2R,4S,5R,6S)-4,5-dimethoxy-2,6-dimethylnon-7-yn-1-yl)-5-methoxyaniline

Guidance literature:: Multi-step reaction with 4 steps

1.1: tert.-butyl lithium / diethyl ether; pentane / 2 h / -78 - 20 °C / Inert atmosphere

1.2: 1 h / -78 °C / Inert atmosphere

2.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.17 h / 20 °C / Inert atmosphere

2.2: 0.25 h / 20 °C / Inert atmosphere

2.3: 0.25 h / 20 °C / Inert atmosphere

3.1: triethyl borane; tri-n-butyl-tin hydride / tetrahydrofuran; toluene / 1 h / 20 °C

4.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; 1,3-dimethylbarbituric acid / dichloromethane / 3 h / 40 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; 1,3-dimethylbarbituric acid; triethyl borane; tert.-butyl lithium; tri-n-butyl-tin hydride; sodium hexamethyldisilazane; In tetrahydrofuran; diethyl ether; dichloromethane; toluene; pentane; 3.1: Barton deoxygenation;
DOI:10.1021/ol2019828

Reference yield:

: C₁₃H₂₂O₃

: 1332626-22-8
3-((2R,4S,5R,6S)-4,5-dimethoxy-2,6-dimethylnon-7-yn-1-yl)-5-methoxyaniline

Guidance literature:: Multi-step reaction with 4 steps

1.1: tert.-butyl lithium / diethyl ether; pentane / 2 h / -78 - 20 °C / Inert atmosphere

1.2: 1 h / -78 °C / Inert atmosphere

2.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.17 h / 20 °C / Inert atmosphere

2.2: 0.25 h / 20 °C / Inert atmosphere

2.3: 0.25 h / 20 °C / Inert atmosphere

3.1: triethyl borane; tri-n-butyl-tin hydride / tetrahydrofuran; toluene / 1 h / 20 °C

4.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; 1,3-dimethylbarbituric acid / dichloromethane / 3 h / 40 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; 1,3-dimethylbarbituric acid; triethyl borane; tert.-butyl lithium; tri-n-butyl-tin hydride; sodium hexamethyldisilazane; In tetrahydrofuran; diethyl ether; dichloromethane; toluene; pentane; 3.1: Barton deoxygenation;
DOI:10.1021/ol2019828