Technology Process of C28H28N6O4S
There total 11 articles about C28H28N6O4S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium hydroxide monohydrate; water;
In
1,4-dioxane;
at 20 ℃;
for 3h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1-methyl-pyrrolidin-2-one / 1.58 h / 19 - 28 °C
2: 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) / tetrahydrofuran / 4 h / 19 °C / Inert atmosphere
3: trifluoroacetic acid / 2 h / 65 °C
4: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C
5: lithium hydroxide monohydrate; water / 1,4-dioxane / 3 h / 20 °C
With
1,3-bis[(diphenylphosphino)propane]dichloronickel(II); lithium hydroxide monohydrate; water; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid;
In
tetrahydrofuran; 1,4-dioxane; 1-methyl-pyrrolidin-2-one; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / tetrahydrofuran / 60 °C / Inert atmosphere
2: hydrogen; 10 wt% Pd(OH)2 on carbon / ethanol; ethyl acetate / 1 h
3: trifluoroacetic acid / 2 h / 65 °C
4: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C
5: lithium hydroxide monohydrate; water / 1,4-dioxane / 3 h / 20 °C
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; lithium hydroxide monohydrate; 10 wt% Pd(OH)2 on carbon; water; hydrogen; triethylamine; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid;
In
tetrahydrofuran; 1,4-dioxane; ethanol; ethyl acetate; N,N-dimethyl-formamide;
