2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol

Base Information Edit

Chemical Name:2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol
CAS No.:1450754-41-2
Molecular Formula:C₇H₁₀N₂O
Molecular Weight:138.169
Hs Code.:
Mol file:1450754-41-2.mol

Synonyms:2-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-ol

Suppliers and Price of 2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol
5mg
$ 65.00

Crysdot
2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol 97%
250mg
$ 452.00

Crysdot
2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol 97%
100mg
$ 282.00

Crysdot
2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol 97%
25mg
$ 142.00

Chemenu
2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol 95%
1g
$ 1066.00

AK Scientific
2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol
1g
$ 1723.00

Total 15 raw suppliers

Chemical Property of 2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol Edit

Chemical Property:

Boiling Point:204.1±36.0 °C(Predicted)
PKA:14.81±0.10(Predicted)
Density:1.08 g/mL
Storage Temp.:-20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Technology Process of 2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol

There total 7 articles about 2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1450754-40-1
1-hydroxy-3-ketohept-6-yne

: 1450754-41-2
2-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-ol

Guidance literature:: 1-hydroxy-3-ketohept-6-yne; With aminosulfonic acid; ammonia;

With iodine;

Reference yield: 38.0%

: 2-(3-(but-3-ynyl)diaziridin-3-yl)ethanol

: 1450754-41-2
2-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-ol

Guidance literature:: With iodine; triethylamine; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere;

Reference yield:

: 100330-50-5
3-oxo-hept-6-ynoic acid methyl ester

: 1450754-41-2
2-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-ol

Guidance literature:: Multi-step reaction with 5 steps

1: toluene-4-sulfonic acid / toluene / 6 h / 120 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 6 h / 0 - 20 °C / Inert atmosphere

3: hydrogenchloride / tetrahydrofuran; water / 16 h / 20 °C / Inert atmosphere

4: ammonia / dichloromethane / 16.25 h / -40 - 20 °C

5: triethylamine; iodine / dichloromethane / 4 h / 20 °C / Inert atmosphere

With hydrogenchloride; lithium aluminium tetrahydride; ammonia; iodine; toluene-4-sulfonic acid; triethylamine; In tetrahydrofuran; dichloromethane; water; toluene;