15-(tert-Butylsulfonyl)-16-phenyltetracyclo<7.5.2.0^1,9.0^2,8>hexadeca-2(8),15-diene

Base Information

• Chemical Name: 15-(tert-Butylsulfonyl)-16-phenyltetracyclo<7.5.2.0^1,9.0^2,8>hexadeca-2(8),15-diene
• CAS No.: 161030-52-0
• Molecular Formula: C₂₆H₃₄O₂S
• Molecular Weight: 410.621
• Mol file: 161030-52-0.mol

Synonyms:15-(tert-Butylsulfonyl)-16-phenyltetracyclo<7.5.2.0^1,9.0^2,8>hexadeca-2(8),15-diene

Chemical Property of 15-(tert-Butylsulfonyl)-16-phenyltetracyclo<7.5.2.0^1,9.0^2,8>hexadeca-2(8),15-diene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 15-(tert-Butylsulfonyl)-16-phenyltetracyclo<7.5.2.0^1,9.0^2,8>hexadeca-2(8),15-diene

There total 4 articles about 15-(tert-Butylsulfonyl)-16-phenyltetracyclo<7.5.2.0^1,9.0^2,8>hexadeca-2(8),15-diene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

phenyllithium (591-51-5) + 15,16-Bis(tert-butylsulfonyl)tetracyclo<7.5.2.0.02,8>hexadeca-2(8),15-diene (161030-49-5) → 15-(tert-Butylsulfonyl)-16-phenyltetracyclo<7.5.2.01,9.02,8>hexadeca-2(8),15-diene (161030-52-0)

Guidance literature:

In tetrahydrofuran; at -78 ℃; for 0.5h;

DOI:10.1039/c39940002049

Reference yield: 14.5%

phenylmagnesium bromide (100-58-3) + 15,16-Bis(tert-butylsulfonyl)tetracyclo<7.5.2.0.02,8>hexadeca-2(8),15-diene (161030-49-5) → 15-(tert-Butylsulfonyl)-16-phenyltetracyclo<7.5.2.01,9.02,8>hexadeca-2(8),15-diene (161030-52-0) + 15,16-Diphenyltetracyclo<7.5.2.01,9.02,8>hexadeca-2(8),15-diene + 16,16'-Diphenylbis(tetracyclo[7.5.2.01,9.02,8]hexadeca-2(8),15-dien-15-yl)

Guidance literature:

palladium(II) acetylacetonate; In tetrahydrofuran; for 1h; Heating;

Reference yield:

1,2-bis(tert-butylsulfonyl)acetylene (129760-76-5) → 15-(tert-Butylsulfonyl)-16-phenyltetracyclo<7.5.2.01,9.02,8>hexadeca-2(8),15-diene (161030-52-0)

Guidance literature:

Multi-step reaction with 2 steps

2: 95 percent / tetrahydrofuran / 0.5 h / -78 °C

In tetrahydrofuran;

DOI:10.1039/c39940002049

upstream raw materials:

phenyllithium

15,16-Bis(tert-butylsulfonyl)tetracyclo<7.5.2.0.0^2,8>hexadeca-2(8),15-diene

phenylmagnesium bromide

1,2-bis(tert-butylsulfonyl)acetylene