methyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(2-naphthylmethyl)-β-D-galactopyranosyl-(1→4)-2,3-O-isopropylidene-1-α-L-rhamnopyranoside

Base Information

Chemical Name:methyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(2-naphthylmethyl)-β-D-galactopyranosyl-(1→4)-2,3-O-isopropylidene-1-α-L-rhamnopyranoside
CAS No.:1380218-22-3
Molecular Formula:C₃₄H₃₉N₃O₉
Molecular Weight:633.698
Hs Code.:

Synonyms:methyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(2-naphthylmethyl)-β-D-galactopyranosyl-(1→4)-2,3-O-isopropylidene-1-α-L-rhamnopyranoside

Suppliers and Price of methyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(2-naphthylmethyl)-β-D-galactopyranosyl-(1→4)-2,3-O-isopropylidene-1-α-L-rhamnopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(2-naphthylmethyl)-β-D-galactopyranosyl-(1→4)-2,3-O-isopropylidene-1-α-L-rhamnopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(2-naphthylmethyl)-β-D-galactopyranosyl-(1→4)-2,3-O-isopropylidene-1-α-L-rhamnopyranoside

There total 5 articles about methyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(2-naphthylmethyl)-β-D-galactopyranosyl-(1→4)-2,3-O-isopropylidene-1-α-L-rhamnopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1380218-33-6
p-tolyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(2-naphthylmethyl)-1-thio-β-D-galactopyranside

: 14133-63-2
methyl 2,3-O-isopropylidene-α-L-rhamnoside

: 1380218-22-3
methyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(2-naphthylmethyl)-β-D-galactopyranosyl-(1→4)-2,3-O-isopropylidene-1-α-L-rhamnopyranoside

Guidance literature:: With N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate; In dichloromethane; acetonitrile; propiononitrile; at -70 - -60 ℃; optical yield given as %de; diastereoselective reaction; Molecular sieve; Inert atmosphere;
DOI:10.1002/ejoc.201200173

Reference yield:

: p-tolyl 2-deoxy-2-azido-1-thio-α/β-D-galactopyranoside

: 1380218-22-3
methyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(2-naphthylmethyl)-β-D-galactopyranosyl-(1→4)-2,3-O-isopropylidene-1-α-L-rhamnopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: toluene-4-sulfonic acid / acetonitrile / 0.5 h / 20 °C

2: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 - 20 °C

3: N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate / dichloromethane; acetonitrile; propiononitrile / -70 - -60 °C / Molecular sieve; Inert atmosphere

With N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate; sodium hydride; toluene-4-sulfonic acid; In dichloromethane; N,N-dimethyl-formamide; acetonitrile; propiononitrile; mineral oil;
DOI:10.1002/ejoc.201200173

Reference yield:

: 84278-00-2
1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-D-galactopyranose

: 1380218-22-3
methyl 2-azido-4,6-O-benzylidene-2-deoxy-3-O-(2-naphthylmethyl)-β-D-galactopyranosyl-(1→4)-2,3-O-isopropylidene-1-α-L-rhamnopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1: boron trifluoride diethyl etherate / dichloromethane / 0.92 h / 20 °C / Sonication

2: methanol; sodium / dichloromethane / 1 h / 20 °C

3: toluene-4-sulfonic acid / acetonitrile / 0.5 h / 20 °C

4: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 0 - 20 °C

5: N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate / dichloromethane; acetonitrile; propiononitrile / -70 - -60 °C / Molecular sieve; Inert atmosphere

With methanol; N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate; boron trifluoride diethyl etherate; sodium; sodium hydride; toluene-4-sulfonic acid; In dichloromethane; N,N-dimethyl-formamide; acetonitrile; propiononitrile; mineral oil;
DOI:10.1002/ejoc.201200173