1-(2-hydroxyethyl)-1-methyl-3-phenylurea

Base Information

• Chemical Name: 1-(2-hydroxyethyl)-1-methyl-3-phenylurea
• CAS No.: 36097-31-1
• Molecular Formula: C10H14N2O2
• Molecular Weight: 194.233
• Mol file: 36097-31-1.mol

Synonyms:1-(2-Hydroxy-ethyl)-1-methyl-3-phenyl-urea;N-Methyl-N-(2-hydroxy-ethyl)-N'-phenyl-harnstoff;

Chemical Property of 1-(2-hydroxyethyl)-1-methyl-3-phenylurea

Chemical Property:

• Vapor Pressure: 1.26E-07mmHg at 25°C
• Boiling Point: 414.8°Cat760mmHg
• Flash Point: 204.7°C
• PSA: 52.57000
• Density: 1.211g/cm³
• LogP: 1.21560

Purity/Quality:

99% ^*data from raw suppliers

1-(2-Hydroxyethyl)-1-methyl-3-phenylurea 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2-hydroxyethyl)-1-methyl-3-phenylurea

There total 2 articles about 1-(2-hydroxyethyl)-1-methyl-3-phenylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2-hydroxyethyl)(methyl)amine (109-83-1) + phenyl isocyanate (103-71-9) → N-Methyl-N-<2-hydroxy-ethyl>-N'-phenyl-harnstoff (36097-31-1)

Guidance literature:

In tetrahydrofuran; at 20 ℃;

DOI:10.1080/00397919908086441

Reference yield:

→ N-Methyl-N-<2-hydroxy-ethyl>-N'-phenyl-harnstoff (36097-31-1)

Guidance literature:

C6H5NCO, (C2H5)2Al-OCH2-CH2-N(CH3)-Al(C2H5)2;

DOI:10.1016/S0022-328X(00)86879-5

Reference yield: 98.0%

N-Methyl-N-<2-hydroxy-ethyl>-N'-phenyl-harnstoff (36097-31-1) → 4,5-dihydro-3-methyl-1-phenylimidazol-2(1H)-one (3363-68-6)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 0.583333h;

DOI:10.1080/00397919908086441

upstream raw materials:

(2-hydroxyethyl)(methyl)amine

phenyl isocyanate

Downstream raw materials:

4,5-dihydro-3-methyl-1-phenylimidazol-2(1H)-one