tert-butyl (3S,4R)-4-(3,4-difluorophenyl)pyrrolidin-3-ylcarbamate

Base Information Edit

Chemical Name:tert-butyl (3S,4R)-4-(3,4-difluorophenyl)pyrrolidin-3-ylcarbamate
CAS No.:1414581-03-5
Molecular Formula:C₁₅H₂₀F₂N₂O₂
Molecular Weight:298.333
Hs Code.:
Mol file:1414581-03-5.mol

Synonyms:tert-butyl (3S,4R)-4-(3,4-difluorophenyl)pyrrolidin-3-ylcarbamate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl (3S,4R)-4-(3,4-difluorophenyl)pyrrolidin-3-ylcarbamate Edit

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Technology Process of tert-butyl (3S,4R)-4-(3,4-difluorophenyl)pyrrolidin-3-ylcarbamate

There total 1 articles about tert-butyl (3S,4R)-4-(3,4-difluorophenyl)pyrrolidin-3-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: C₁₅H₁₈F₂N₂O₅

: 1414581-03-5
tert-butyl (3S,4R)-4-(3,4-difluorophenyl)pyrrolidin-3-ylcarbamate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃;

Reference yield: 96.0%

: 1414581-03-5
tert-butyl (3S,4R)-4-(3,4-difluorophenyl)pyrrolidin-3-ylcarbamate

: 501-53-1,94274-21-2
benzyl chloroformate

: C₁₈H₁₈F₂N₂O₂*ClH

Guidance literature:: tert-butyl (3S,4R)-4-(3,4-difluorophenyl)pyrrolidin-3-ylcarbamate; benzyl chloroformate; With triethylamine; In dichloromethane; at 20 ℃; for 2h; Cooling with ice;

With hydrogenchloride; In ethyl acetate; for 5h;