Technology Process of Dibenzyl-((S)-3-methyl-1-(S)-oxiranyl-butyl)-amine
There total 13 articles about Dibenzyl-((S)-3-methyl-1-(S)-oxiranyl-butyl)-amine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Sm / tetrahydrofuran / 0.33 h / 0 °C
2: NaH / CH2Cl2 / 0.5 h / Ambient temperature
With
samarium; sodium hydride;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/jo970318i
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 89 percent / K2CO3 / ethanol / 72 h / Ambient temperature
2: pyridine-sulfur trioxide, Et3N / dimethylsulfoxide / 2.5 h / 10 - 15 °C
3: 1) Li / 1) THF, -75 deg C, 75 min, 2) THF, 20 deg C, 15-20 min
With
sulfur trioxide pyridine complex; lithium; potassium carbonate; triethylamine;
In
ethanol; dimethyl sulfoxide;
DOI:10.1021/jo960109i
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 89 percent / K2CO3 / ethanol / 72 h / Ambient temperature
2: pyridine-sulfur trioxide, Et3N / dimethylsulfoxide / 2.5 h / 10 - 15 °C
3: 1) Li / 1) THF, -75 deg C, 75 min, 2) THF, 20 deg C, 15-20 min
With
sulfur trioxide pyridine complex; lithium; potassium carbonate; triethylamine;
In
ethanol; dimethyl sulfoxide;
DOI:10.1021/jo960109i
