C₂₆H₂₅BrO₇

Base Information

• Chemical Name: C₂₆H₂₅BrO₇
• CAS No.: 253590-01-1
• Molecular Formula: C₂₆H₂₅BrO₇
• Molecular Weight: 529.384
• Mol file: 253590-01-1.mol

Synonyms:C₂₆H₂₅BrO₇

Chemical Property of C₂₆H₂₅BrO₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₂₅BrO₇

There total 12 articles about C₂₆H₂₅BrO₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

benzoyl chloride (98-88-4) + C19H21BrO6 (253589-99-0) → C26H25BrO7 (253590-01-1)

Guidance literature:

With pyridine; dmap;

DOI:10.1039/a905631i

Reference yield:

benzoyl chloride (98-88-4) → C26H25BrO7 (253590-01-1)

Guidance literature:

Multi-step reaction with 5 steps

1: 90 percent / DMAP; pyridine

2: 91 percent / MCPBA / CH₂Cl₂ / 20 °C

3: BF₃*OEt₂ / toluene / -20 °C

4: HF / acetonitrile; tetrahydrofuran / 30 °C

5: 52 percent / DMAP; pyridine

With pyridine; dmap; boron trifluoride diethyl etherate; hydrogen fluoride; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; toluene; acetonitrile; 1: Acylation / 2: Epoxidation / 3: Ring cleavage / 4: Desilylation / 5: Acylation;

DOI:10.1039/a905631i

Reference yield:

(+)-(1R,4S,4aR,5S,8aS)-5-tert-Butyldimethylsilyloxy-1,4,4a,6,7,8-hexahydro-endo-1,4-methanonaphthalen-8(5H)-one (194796-30-0) → C26H25BrO7 (253590-01-1)

Guidance literature:

Multi-step reaction with 11 steps

1: 89 percent / NaH / tetrahydrofuran / 20 °C

2: 82 percent / O₂; KF; (EtO)3P / dimethylsulfoxide

3: NaBH₄ / methanol; tetrahydrofuran / -15 °C

4: NBS / CH₂Cl₂ / -15 °C

5: 84 percent / POCl₃; pyridine / 50 °C

6: DIBAL-H / toluene / -78 °C

7: 90 percent / DMAP; pyridine

8: 91 percent / MCPBA / CH₂Cl₂ / 20 °C

9: BF₃*OEt₂ / toluene / -20 °C

10: HF / acetonitrile; tetrahydrofuran / 30 °C

11: 52 percent / DMAP; pyridine

With pyridine; dmap; potassium fluoride; sodium tetrahydroborate; N-Bromosuccinimide; boron trifluoride diethyl etherate; hydrogen fluoride; oxygen; sodium hydride; diisobutylaluminium hydride; 3-chloro-benzenecarboperoxoic acid; triethyl phosphite; trichlorophosphate; In tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide; toluene; acetonitrile; 1: Condensation / 2: Oxidation / 3: Reduction / 4: Bromination / 5: Dehydration / 6: Reduction / 7: Acylation / 8: Epoxidation / 9: Ring cleavage / 10: Desilylation / 11: Acylation;

DOI:10.1039/a905631i

upstream raw materials:

benzoyl chloride

C₁₉H₂₁BrO₆

(+)-(1R,4S,4aR,5S,8aS)-5-tert-Butyldimethylsilyloxy-1,4,4a,6,7,8-hexahydro-endo-1,4-methanonaphthalen-8(5H)-one

C₁₈H₂₉BrO₃Si

Downstream raw materials:

C₂₆H₂₆O₇