11-Ketoandrosterone

Base Information

Chemical Name:11-Ketoandrosterone
CAS No.:1231-82-9
Molecular Formula:C19H28 O3
Molecular Weight:304.42
Hs Code.:
NSC Number:56412
UNII:3T4E87JT27
DSSTox Substance ID:DTXSID901043038
Nikkaji Number:J104.139H
Wikipedia:11-Ketoandrosterone
Wikidata:Q27115836
Mol file:1231-82-9.mol

Synonyms:11-ketoandrosterone

Suppliers and Price of 11-Ketoandrosterone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
11-OxoAndrosterone
25mg
$ 330.00

American Custom Chemicals Corporation
11-OXO ANDROSTERONE 95.00%
100MG
$ 2055.90

AHH
11-Ketoandrosterone 98%
0.5g
$ 478.00

Total 12 raw suppliers

Chemical Property of 11-Ketoandrosterone

Chemical Property:

Vapor Pressure:3.97E-10mmHg at 25°C
Melting Point:143-146°C
Boiling Point:453.4°Cat760mmHg
Flash Point:242.1°C
PSA：54.37000
Density:1.152g/cm³
LogP:3.13810
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:304.20384475
Heavy Atom Count:22
Complexity:527

Purity/Quality:

97% ^*data from raw suppliers

11-OxoAndrosterone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC(CC1CCC3C2C(=O)CC4(C3CCC4=O)C)O
Isomeric SMILES:C[C@]12CC[C@H](C[C@@H]1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CCC4=O)C)O
Uses A metabolite of Androsterone (A637535).

Technology Process of 11-Ketoandrosterone

There total 16 articles about 11-Ketoandrosterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1429-06-7,53861-56-6,54323-42-1,102207-99-8,1482-70-8
5α-androstane-3,11,17-trione

: 1231-82-9
(3α,5α)-3-hydroxyandrostane-11,17-dione

Guidance literature:: 5α-androstane-3,11,17-trione; With potassium tri-sec-butyl-borohydride; In tetrahydrofuran; at -78 ℃; for 1.5h;

With water;
DOI:10.1021/jm2014925

Reference yield:

: 382-45-6
adrenosterone

: 1231-82-9
(3α,5α)-3-hydroxyandrostane-11,17-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Li/NH₃, 2.) CrO/H₂SO₄

2: 47 percent / K-Selectride / tetrahydrofuran / 1.) -78 deg C, 3 h, 2.) RT, 20 min

With chromium oxide; sulfuric acid; ammonia; lithium; potassium tri-sec-butyl-borohydride; In tetrahydrofuran;
DOI:10.1021/ja00037a013