(Z)-2-(2-oxoindolin-3-ylidene)-2-(4-(trifluoromethyl)phenyl)acetonitrile

Base Information

Chemical Name:(Z)-2-(2-oxoindolin-3-ylidene)-2-(4-(trifluoromethyl)phenyl)acetonitrile
CAS No.:1262120-74-0
Molecular Formula:C₁₇H₉F₃N₂O
Molecular Weight:314.266
Hs Code.:

Synonyms:(Z)-2-(2-oxoindolin-3-ylidene)-2-(4-(trifluoromethyl)phenyl)acetonitrile

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Chemical Property of (Z)-2-(2-oxoindolin-3-ylidene)-2-(4-(trifluoromethyl)phenyl)acetonitrile

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Technology Process of (Z)-2-(2-oxoindolin-3-ylidene)-2-(4-(trifluoromethyl)phenyl)acetonitrile

There total 3 articles about (Z)-2-(2-oxoindolin-3-ylidene)-2-(4-(trifluoromethyl)phenyl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: copper(l) cyanide

: C₁₆H₈F₃NO

: 1262120-74-0
(Z)-2-(2-oxoindolin-3-ylidene)-2-(4-(trifluoromethyl)phenyl)acetonitrile

Guidance literature:: With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; trifuran-2-yl-phosphane; In 1,4-dioxane; at 100 ℃; for 2h; optical yield given as %de; stereoselective reaction;
DOI:10.1246/cl.2010.1132

Reference yield: 78.0%

: 7677-24-9
trimethylsilyl cyanide

: 1148119-02-1
(E)-3-(4-(trifluoromethyl)benzylidene)indolin-2-one

: 1262120-74-0
(Z)-2-(2-oxoindolin-3-ylidene)-2-(4-(trifluoromethyl)phenyl)acetonitrile

Guidance literature:: With cerium(III) chloride heptahydrate; potassium hydroxide; In water; at 100 ℃; for 2h; Green chemistry;
DOI:10.1080/00397911.2018.1540050

Reference yield: 73.0%

: 613-90-1
benzoyl cyanide

: 1148119-02-1
(E)-3-(4-(trifluoromethyl)benzylidene)indolin-2-one

: 1262120-74-0
(Z)-2-(2-oxoindolin-3-ylidene)-2-(4-(trifluoromethyl)phenyl)acetonitrile

Guidance literature:: With potassium carbonate; potassium hydroxide; In water; acetonitrile; at 80 ℃; for 3h; stereoselective reaction;
DOI:10.1016/j.tet.2018.01.050