2-[2-(2-methyl-phenyl)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

• Chemical Name: 2-[2-(2-methyl-phenyl)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS No.: 1431792-80-1
• Molecular Formula: C₁₅H₂₃BO₂
• Molecular Weight: 246.157
• Mol file: 1431792-80-1.mol

Synonyms:2-[2-(2-methyl-phenyl)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property of 2-[2-(2-methyl-phenyl)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[2-(2-methyl-phenyl)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 5 articles about 2-[2-(2-methyl-phenyl)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-methyl-2-vinyl-benzene (611-15-4) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 2-[2-(2-methyl-phenyl)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1431792-80-1)

Guidance literature:

With calcium chloride; In chloroform-d1; at 110 ℃; for 12h; Glovebox;

Reference yield: 82.0%

1-(2-bromoethyl)-2-methylbenzene (16793-90-1) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 2-[2-(2-methyl-phenyl)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1431792-80-1)

Guidance literature:

With chromium chloride; aluminium; 4,4'-di-tert-butyl-2,2'-bipyridine; In tetrahydrofuran; at 80 ℃; for 15h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.organomet.1c00171

Reference yield: 80.0%

1-methyl-2-vinyl-benzene (611-15-4) + bis(pinacol)diborane (73183-34-3) → 2-[2-(2-methyl-phenyl)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1431792-80-1)

Guidance literature:

With sodium methylate; copper(l) chloride; In methanol; at 40 ℃; for 10h; regioselective reaction;

DOI:10.1021/jo502606x

upstream raw materials:

1-methyl-2-vinyl-benzene

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

bis(pinacol)diborane

1-(2-bromoethyl)-2-methylbenzene