2-(3,4-bis(tetrahydropyran-2-yloxy)phenyl)-2-(tetrahydropyran-2-yloxy)acetaldehyde

Base Information

Chemical Name:2-(3,4-bis(tetrahydropyran-2-yloxy)phenyl)-2-(tetrahydropyran-2-yloxy)acetaldehyde
CAS No.:582289-88-1
Molecular Formula:C₂₃H₃₂O₇
Molecular Weight:420.503
Hs Code.:

Synonyms:2-(3,4-bis(tetrahydropyran-2-yloxy)phenyl)-2-(tetrahydropyran-2-yloxy)acetaldehyde

Suppliers and Price of 2-(3,4-bis(tetrahydropyran-2-yloxy)phenyl)-2-(tetrahydropyran-2-yloxy)acetaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(3,4-bis(tetrahydropyran-2-yloxy)phenyl)-2-(tetrahydropyran-2-yloxy)acetaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(3,4-bis(tetrahydropyran-2-yloxy)phenyl)-2-(tetrahydropyran-2-yloxy)acetaldehyde

There total 5 articles about 2-(3,4-bis(tetrahydropyran-2-yloxy)phenyl)-2-(tetrahydropyran-2-yloxy)acetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 582289-87-0
2-(3,4-bis(tetrahydropyran-2-yloxy)phenyl)-2-(tetrahydropyran-2-yloxy)acetic acid methyl ester

: 582289-88-1
2-(3,4-bis(tetrahydropyran-2-yloxy)phenyl)-2-(tetrahydropyran-2-yloxy)acetaldehyde

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; toluene; at -78 ℃; for 2h;
DOI:10.1016/S0045-2068(03)00019-1

Reference yield:

: 102-32-9
3,4-dihydroxyphenylacetate

: 582289-88-1
2-(3,4-bis(tetrahydropyran-2-yloxy)phenyl)-2-(tetrahydropyran-2-yloxy)acetaldehyde

Guidance literature:: Multi-step reaction with 5 steps

1: conc. H₂SO₄ / Heating

2: pyridinium p-tosylate / CH₂Cl₂ / 1 h

3: 85 percent / KHMDS; 2-sulfonyloxaziridine / tetrahydrofuran; toluene / 0.33 h / -78 °C

4: 91 percent / pyridinium p-toluenesulfonate / CH₂Cl₂ / 20 °C

5: 93 percent / DIBALH / toluene; CH₂Cl₂ / 2 h / -78 °C

With 2-sulfonyloxaziridine; sulfuric acid; pyridinium p-toluenesulfonate; potassium hexamethylsilazane; diisobutylaluminium hydride; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1016/S0045-2068(03)00019-1

Reference yield:

: 25379-88-8
2-(3,4-dihydroxyphenyl)acetic acid methyl ester

: 582289-88-1
2-(3,4-bis(tetrahydropyran-2-yloxy)phenyl)-2-(tetrahydropyran-2-yloxy)acetaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: pyridinium p-tosylate / CH₂Cl₂ / 1 h

2: 85 percent / KHMDS; 2-sulfonyloxaziridine / tetrahydrofuran; toluene / 0.33 h / -78 °C

3: 91 percent / pyridinium p-toluenesulfonate / CH₂Cl₂ / 20 °C

4: 93 percent / DIBALH / toluene; CH₂Cl₂ / 2 h / -78 °C

With 2-sulfonyloxaziridine; pyridinium p-toluenesulfonate; potassium hexamethylsilazane; diisobutylaluminium hydride; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1016/S0045-2068(03)00019-1