3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetic Acid Methyl Ester

Base Information

Chemical Name:3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetic Acid Methyl Ester
CAS No.:582289-84-7
Molecular Formula:C₁₉H₂₆O₆
Molecular Weight:350.412
Hs Code.:
Mol file:582289-84-7.mol

Synonyms:3,4-bis(tetrahydropyran-2-yloxy)phenylacetic acid methyl ester

Suppliers and Price of 3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetic Acid Methyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneaceticAcidMethylEster
2.5g
$ 1320.00

Medical Isotopes, Inc.
3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneaceticAcidMethylEster
250 mg
$ 650.00

Total 2 raw suppliers

Chemical Property of 3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetic Acid Methyl Ester

Chemical Property:

Boiling Point:479.7±45.0 °C(Predicted)
Density:1.178±0.06 g/cm3(Predicted)
Solubility.:DCM

Purity/Quality:

99% ^*data from raw suppliers

3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneaceticAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetic Acid Methyl Ester i s an intermediate in the synthesis of Dopal (D533885), the reactive metabolite of dopamine (D533780), an endogenous catecholamine with α and β-adrenergic activity.

Technology Process of 3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetic Acid Methyl Ester

There total 2 articles about 3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetic Acid Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110-87-2
3,4-dihydro-2H-pyran

: 25379-88-8
2-(3,4-dihydroxyphenyl)acetic acid methyl ester

: 582289-84-7
3,4-bis(tetrahydropyran-2-yloxy)phenylacetic acid methyl ester

Guidance literature:: With pyridinium p-toluenesulfonate; In dichloromethane; for 1h;
DOI:10.1016/S0045-2068(03)00019-1

Reference yield:

: 102-32-9
3,4-dihydroxyphenylacetate

: 582289-84-7
3,4-bis(tetrahydropyran-2-yloxy)phenylacetic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: conc. H₂SO₄ / Heating

2: pyridinium p-tosylate / CH₂Cl₂ / 1 h

With sulfuric acid; pyridinium p-toluenesulfonate; In dichloromethane;
DOI:10.1016/S0045-2068(03)00019-1

Reference yield: 85.0%

: 582289-84-7
3,4-bis(tetrahydropyran-2-yloxy)phenylacetic acid methyl ester

: 582289-86-9
2-(3,4-bis(tetrahydropyran-2-yloxy)phenyl)-2-hydroxyacetic acid methyl ester

Guidance literature:: With 2-sulfonyloxaziridine; potassium hexamethylsilazane; In tetrahydrofuran; toluene; at -78 ℃; for 0.333333h;
DOI:10.1016/S0045-2068(03)00019-1