2,2'-(diphenylphosphinoyl)-3,3',6,6'-tetramethoxybiphenyl

Base Information

• Chemical Name: 2,2'-(diphenylphosphinoyl)-3,3',6,6'-tetramethoxybiphenyl
• CAS No.: 136202-13-6
• Molecular Formula: C₄₀H₃₆O₆P₂
• Molecular Weight: 674.67
• Mol file: 136202-13-6.mol

Synonyms:2,2'-(diphenylphosphinoyl)-3,3',6,6'-tetramethoxybiphenyl

Chemical Property of 2,2'-(diphenylphosphinoyl)-3,3',6,6'-tetramethoxybiphenyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 2,2'-(diphenylphosphinoyl)-3,3',6,6'-tetramethoxybiphenyl

There total 2 articles about 2,2'-(diphenylphosphinoyl)-3,3',6,6'-tetramethoxybiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(3,6-dimethoxy-2-iodophenyl)diphenylphosphine oxide (136202-05-6) → 2,2'-(diphenylphosphinoyl)-3,3',6,6'-tetramethoxybiphenyl (136202-13-6)

Guidance literature:

With copper; In N,N-dimethyl-formamide; at 155 ℃; for 8h;

DOI:10.1021/jo00024a019

Reference yield:

(2,5-dimethoxyphenyl)diphenylphosphine oxide (72666-56-9) → 2,2'-(diphenylphosphinoyl)-3,3',6,6'-tetramethoxybiphenyl (136202-13-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) tBuLi, 2) I₂ / 1) pentane, THF, a) -100 to -70 deg C, 30 min, b) -70 deg C, 3.5 h, 2) THF, -70 to 0 deg C

2: 85 percent / Cu-powder / dimethylformamide / 8 h / 155 °C

With iodine; tert.-butyl lithium; copper; In N,N-dimethyl-formamide;

DOI:10.1021/jo00024a019

Reference yield: 90.0%

2,2'-(diphenylphosphinoyl)-3,3',6,6'-tetramethoxybiphenyl (136202-13-6) → C40H36O4P2 (1229028-54-9,428874-77-5,428875-76-7)

Guidance literature:

With trichlorosilane; triethylamine; In toluene; for 3h; Reflux;

DOI:10.1016/j.tetlet.2010.03.029

upstream raw materials:

(3,6-dimethoxy-2-iodophenyl)diphenylphosphine oxide

(2,5-dimethoxyphenyl)diphenylphosphine oxide

Downstream raw materials:

C₄₀H₃₆O₄P₂