1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-4-fluoro-1-piperidinecarboxylate

Base Information

Chemical Name:1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-4-fluoro-1-piperidinecarboxylate
CAS No.:645379-04-0
Molecular Formula:C₂₀H₂₆F₂N₂O₂
Molecular Weight:364.435
Hs Code.:

Synonyms:1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-4-fluoro-1-piperidinecarboxylate

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Chemical Property of 1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-4-fluoro-1-piperidinecarboxylate

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Technology Process of 1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-4-fluoro-1-piperidinecarboxylate

There total 1 articles about 1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-4-fluoro-1-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 645379-02-8
1,1-dimethylethyl-4-[2-cyano-3-(ethyloxy)-1-(4-fluoro-2-methylphenyl)-3-oxopropyl]-4-fluoro-1-piperidinecarboxylate

: 645379-04-0
1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-4-fluoro-1-piperidinecarboxylate

Guidance literature:: With water; sodium chloride; In dimethyl sulfoxide; at 160 ℃; for 2h;

Reference yield:

: 645379-04-0
1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-4-fluoro-1-piperidinecarboxylate

: 645379-06-2
3-(1-{[(1,1-dimethylethyl)oxy]carbonyl}-4-fluoro-4-piperidinyl)-3-(4-fluoro-2-methylphenyl) propanoic acid

Guidance literature:: 1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-4-fluoro-1-piperidinecarboxylate; With potassium hydroxide; In ethanol; water; at 150 ℃; for 0.583333h; under 4654.46 Torr;

With hydrogenchloride; In ethanol; water; pH=4 / 5; citrate-hydrochloric acid buffer solution;