4-((5-Nitro-1H-indol-3-yl)methyl)morpholine

Base Information

Chemical Name:4-((5-Nitro-1H-indol-3-yl)methyl)morpholine
CAS No.:3414-70-8
Molecular Formula:C13H15N3O3
Molecular Weight:261.2765
Hs Code.:2934999090
DSSTox Substance ID:DTXSID50187734
Nikkaji Number:J41.070E
Wikidata:Q83059453
Mol file:3414-70-8.mol

Synonyms:3414-70-8;4-((5-Nitro-1H-indol-3-yl)methyl)morpholine;BRN 1592116;3-(Morpholinomethyl)-5-nitroindole;5-Nitro-3-(morpholinomethyl)indole;INDOLE, 3-(MORPHOLINOMETHYL)-5-NITRO-;3-(4-Morpholinylmethyl)-5-nitro-1H-indole;SCHEMBL19252919;DTXSID50187734;MFCD01718613;LS-83312;1H-Indole, 3-(4-morpholinylmethyl)-5-nitro-;3-[(morpholin-4-yl)methyl]-5-nitro-1H-indole

Suppliers and Price of 4-((5-Nitro-1H-indol-3-yl)methyl)morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
4-((5-nitro-1H-indol-3-yl)methyl)morpholine AldrichCPR
1g
$ 168.00

Crysdot
4-((5-Nitro-1H-indol-3-yl)methyl)morpholine 97%
5g
$ 913.00

Crysdot
4-((5-Nitro-1H-indol-3-yl)methyl)morpholine 97%
1g
$ 304.00

Chemenu
4-((5-Nitro-1H-indol-3-yl)methyl)morpholine 95%+
1g
$ 287.00

Chemenu
4-((5-Nitro-1H-indol-3-yl)methyl)morpholine 95%+
5g
$ 861.00

Alichem
4-((5-Nitro-1H-indol-3-yl)methyl)morpholine
5g
$ 687.48

Total 7 raw suppliers

Chemical Property of 4-((5-Nitro-1H-indol-3-yl)methyl)morpholine

Chemical Property:

Vapor Pressure:1.27E-08mmHg at 25°C
Boiling Point:459.3°Cat760mmHg
Flash Point:231.6°C
PSA：74.08000
Density:1.366g/cm³
LogP:2.36940
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:261.11134135
Heavy Atom Count:19
Complexity:328

Purity/Quality:

98%min ^*data from raw suppliers

4-((5-nitro-1H-indol-3-yl)methyl)morpholine AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1CC2=CNC3=C2C=C(C=C3)[N+](=O)[O-]

Technology Process of 4-((5-Nitro-1H-indol-3-yl)methyl)morpholine

There total 1 articles about 4-((5-Nitro-1H-indol-3-yl)methyl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 110-91-8,99108-56-2
morpholine

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 6146-52-7
5-nitroindole

: 3414-70-8
4-((5-nitro-1H-indol-3-yl)methyl)morpholine

Guidance literature:: With acetic acid; at 35 ℃;
DOI:10.1016/j.ejmech.2017.08.031

Reference yield:

: 3414-70-8
4-((5-nitro-1H-indol-3-yl)methyl)morpholine

: 1-benzyl-N-(3-(morpholinomethyl)-1H-indol-5-yl)-1H-pyrazole-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / methanol / 20 °C / Reflux

2: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / N,N-dimethyl-formamide / 4 h / 20 °C

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; hydrazine hydrate; triethylamine; In methanol; N,N-dimethyl-formamide;

Reference yield:

: 3414-70-8
4-((5-nitro-1H-indol-3-yl)methyl)morpholine

: methyl (Z)-3-(((3-(morpholinomethyl)-1H-indol-5-yl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: palladium on activated carbon; hydrogen / ethanol / 6 h / 20 °C

2: methanol / Reflux

With palladium on activated carbon; hydrogen; In methanol; ethanol;
DOI:10.1016/j.ejmech.2017.08.031