1-acetyl-α-<methyl>-2,3-dihydro-7-nitro-1H-indole-5-methanol acetate ester

Base Information

Chemical Name:1-acetyl-α-<methyl>-2,3-dihydro-7-nitro-1H-indole-5-methanol acetate ester
CAS No.:101629-42-9
Molecular Formula:C₂₈H₂₉N₃O₅
Molecular Weight:487.555
Hs Code.:

1-acetyl-α-<<bis(phenylmethyl)amino>methyl>-2,3-dihydro-7-nitro-1H-indole-5-methanol acetate ester

Synonyms:1-acetyl-α-<methyl>-2,3-dihydro-7-nitro-1H-indole-5-methanol acetate ester

Suppliers and Price of 1-acetyl-α-<methyl>-2,3-dihydro-7-nitro-1H-indole-5-methanol acetate ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-acetyl-α-<methyl>-2,3-dihydro-7-nitro-1H-indole-5-methanol acetate ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-acetyl-α-<methyl>-2,3-dihydro-7-nitro-1H-indole-5-methanol acetate ester

There total 5 articles about 1-acetyl-α-<methyl>-2,3-dihydro-7-nitro-1H-indole-5-methanol acetate ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.9%

: 101544-40-5
1-acetyl-α-<methyl>-2,3-dihydro-1H-indole-5-methanol acetate ester

: 101629-42-9
1-acetyl-α-<methyl>-2,3-dihydro-7-nitro-1H-indole-5-methanol acetate ester

Guidance literature:: With nitric acid; In acetic acid; for 6h; Ambient temperature;
DOI:10.1021/jm00156a019

Reference yield:

: 16078-30-1
1-Acetyl-2,3-dihydro-1H-indole

: 101629-42-9
1-acetyl-α-<methyl>-2,3-dihydro-7-nitro-1H-indole-5-methanol acetate ester

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) aluminum chloride / 1.) 1,2-dichloroethane, 20 min, 2.) 1,2-dichloroethane, 50 deg C, 1 h

2: dimethylformamide / 2 h / 60 °C

3: NaBH₄ / ethanol / 1.) RT, 4.5 h, 2.) 50 deg C, 1 h

4: 94.5 percent / pyridine / Ambient temperature

5: 85.9 percent / 90percent nitric acid / acetic acid / 6 h / Ambient temperature

With pyridine; sodium tetrahydroborate; aluminium trichloride; nitric acid; In ethanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00156a019

Reference yield:

: 76139-03-2
2-chloro-1-(1-acetyl-2,3-dihydroindole-5-yl)ethanone

: 101629-42-9
1-acetyl-α-<methyl>-2,3-dihydro-7-nitro-1H-indole-5-methanol acetate ester

Guidance literature:: Multi-step reaction with 4 steps

1: dimethylformamide / 2 h / 60 °C

2: NaBH₄ / ethanol / 1.) RT, 4.5 h, 2.) 50 deg C, 1 h

3: 94.5 percent / pyridine / Ambient temperature

4: 85.9 percent / 90percent nitric acid / acetic acid / 6 h / Ambient temperature

With pyridine; sodium tetrahydroborate; nitric acid; In ethanol; acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00156a019