3-[(1-cyano-7-cyclohexyloxy-4-hydroxy-isoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Base Information

Chemical Name:3-[(1-cyano-7-cyclohexyloxy-4-hydroxy-isoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid
CAS No.:1455090-28-4
Molecular Formula:C₂₂H₂₅N₃O₅
Molecular Weight:411.458
Hs Code.:

Synonyms:3-[(1-cyano-7-cyclohexyloxy-4-hydroxy-isoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Suppliers and Price of 3-[(1-cyano-7-cyclohexyloxy-4-hydroxy-isoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-[(1-cyano-7-cyclohexyloxy-4-hydroxy-isoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-[(1-cyano-7-cyclohexyloxy-4-hydroxy-isoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

There total 3 articles about 3-[(1-cyano-7-cyclohexyloxy-4-hydroxy-isoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

: 1455094-67-3
3-[(1-cyano-7-cyclohexyloxy-4-hydroxy-isoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid tert-butyl ester

: 1455090-28-4
3-[(1-cyano-7-cyclohexyloxy-4-hydroxy-isoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 3h;

Reference yield:

: 75235-66-4
cyano-dimethylacetic acid tert-butyl ester

: 1455090-28-4
3-[(1-cyano-7-cyclohexyloxy-4-hydroxy-isoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen / methanol / 20 °C

2: 1 h / 140 °C / Microwave irradiation

3: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

With hydrogen; trifluoroacetic acid; In methanol; dichloromethane;

Reference yield:

: 259794-53-1
3-amino-2,2-dimethylpropionic acid tert-butyl ester

: 1455090-28-4
3-[(1-cyano-7-cyclohexyloxy-4-hydroxy-isoquinoline-3-carbonyl)amino]-2,2-dimethylpropionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1 h / 140 °C / Microwave irradiation

2: trifluoroacetic acid / dichloromethane / 3 h / 20 °C

With trifluoroacetic acid; In dichloromethane;