5-[(5-chloro-2-hydroxyphenyl)methyl]-N-(2,6-diflorophenyl)-2-furancarboxamide

Base Information

Chemical Name:5-[(5-chloro-2-hydroxyphenyl)methyl]-N-(2,6-diflorophenyl)-2-furancarboxamide
CAS No.:913957-58-1
Molecular Formula:C₁₈H₁₂ClF₂NO₃
Molecular Weight:363.748
Hs Code.:

Synonyms:5-[(5-chloro-2-hydroxyphenyl)methyl]-N-(2,6-diflorophenyl)-2-furancarboxamide

Suppliers and Price of 5-[(5-chloro-2-hydroxyphenyl)methyl]-N-(2,6-diflorophenyl)-2-furancarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 5-[(5-chloro-2-hydroxyphenyl)methyl]-N-(2,6-diflorophenyl)-2-furancarboxamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 5-[(5-chloro-2-hydroxyphenyl)methyl]-N-(2,6-diflorophenyl)-2-furancarboxamide

There total 7 articles about 5-[(5-chloro-2-hydroxyphenyl)methyl]-N-(2,6-diflorophenyl)-2-furancarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 913957-57-0
4-chloro-2-[(5-{[(2,6-difluorophenyl)amino]carbonyl}-2-furanyl)methyl]phenylacetate

: 913957-58-1
5-[(5-chloro-2-hydroxyphenyl)methyl]-N-(2,6-diflorophenyl)-2-furancarboxamide

Guidance literature:: 4-chloro-2-[(5-{[(2,6-difluorophenyl)amino]carbonyl}-2-furanyl)methyl]phenylacetate; With sodium hydroxide; ethanol; water; at 20 ℃; for 18h;

With hydrogenchloride; In diethyl ether;

Reference yield:

: 913957-55-8
5-[(5-chloro-2-hydroxyphenyl)methyl]-2-furancarboxylic acid

: 913957-58-1
5-[(5-chloro-2-hydroxyphenyl)methyl]-N-(2,6-diflorophenyl)-2-furancarboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 0.5 h / 80 °C

2: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 1.5 h / 20 °C

3: pyridine / dichloromethane / 0.58 h / 20 °C

4: sodium hydroxide; ethanol; water / 18 h / 20 °C

With pyridine; sodium hydroxide; oxalyl dichloride; ethanol; water; N,N-dimethyl-formamide; In dichloromethane;

Reference yield:

: 913957-28-5
ethyl 5-[(5-chloro-2-hydroxyphenyl)methyl]-2-furancarboxylate

: 913957-58-1
5-[(5-chloro-2-hydroxyphenyl)methyl]-N-(2,6-diflorophenyl)-2-furancarboxamide

Guidance literature:: Multi-step reaction with 5 steps

1: sodium hydroxide; ethanol; water / 20 °C

2: pyridine / 0.5 h / 80 °C

3: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 1.5 h / 20 °C

4: pyridine / dichloromethane / 0.58 h / 20 °C

5: sodium hydroxide; ethanol; water / 18 h / 20 °C

With pyridine; sodium hydroxide; oxalyl dichloride; ethanol; water; N,N-dimethyl-formamide; In dichloromethane;