IDD₃₈₈

Base Information

• Chemical Name: IDD₃₈₈
• CAS No.: 314297-26-2
• Molecular Formula: C₁₆H₁₂BrClFNO₄
• Molecular Weight: 416.631
• Mol file: 314297-26-2.mol

Synonyms:IDD₃₈₈

Chemical Property of IDD₃₈₈

Chemical Property:

• Boiling Point: 574.5±50.0 °C(Predicted)
• Density: 1.615±0.06 g/cm3(Predicted)

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of IDD₃₈₈

There total 4 articles about IDD₃₈₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

[2-(4-bromo-2-fluoro-benzylcarbamoyl)-5-chloro-phenoxy]-acetic acid ethyl ester (314297-96-6) → IDD388 (314297-26-2)

Guidance literature:

With aq NaOH; In ethanol;

Reference yield:

4-chlorosalicylic acid (5106-98-9) → IDD388 (314297-26-2)

Guidance literature:

Multi-step reaction with 4 steps

1: thionyl chloride; N,N-dimethylformamide / heptane / 60 °C

2: N,N-diisopropylethylamine / CH₂Cl₂ / 20 °C

3: aq. K₂CO₃ / acetone / 50 °C

4: aq. NaOH / ethanol

With sodium hydroxide; thionyl chloride; potassium carbonate; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; In ethanol; n-heptane; dichloromethane; acetone;

DOI:10.1016/j.bmc.2004.07.062

Reference yield:

4-chloro-2-hydroxybenzoyl chloride (82944-13-6) → IDD388 (314297-26-2)

Guidance literature:

Multi-step reaction with 3 steps

1: N,N-diisopropylethylamine / CH₂Cl₂ / 20 °C

2: aq. K₂CO₃ / acetone / 50 °C

3: aq. NaOH / ethanol

With sodium hydroxide; potassium carbonate; N-ethyl-N,N-diisopropylamine; In ethanol; dichloromethane; acetone;

DOI:10.1016/j.bmc.2004.07.062

upstream raw materials:

[2-(4-bromo-2-fluoro-benzylcarbamoyl)-5-chloro-phenoxy]-acetic acid ethyl ester

4-chlorosalicylic acid

4-chloro-2-hydroxybenzoyl chloride

N-(4-bromo-2-fluoro-benzyl)-4-chloro-2-hydroxy-benzamide

Refernces

• 1、 -. "Substituted phenoxyacetic acids". . . Retrieved 2008/06/13.