N-[3-(tert-butyldimethylsilyl)-2-propynyl]-N-2-propenyl-p-toluenesulfonamide

Base Information

• Chemical Name: N-[3-(tert-butyldimethylsilyl)-2-propynyl]-N-2-propenyl-p-toluenesulfonamide
• CAS No.: 1202400-45-0
• Molecular Formula: C₁₉H₂₉NO₂SSi
• Molecular Weight: 363.596
• Mol file: 1202400-45-0.mol

Synonyms:N-[3-(tert-butyldimethylsilyl)-2-propynyl]-N-2-propenyl-p-toluenesulfonamide

Chemical Property of N-[3-(tert-butyldimethylsilyl)-2-propynyl]-N-2-propenyl-p-toluenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[3-(tert-butyldimethylsilyl)-2-propynyl]-N-2-propenyl-p-toluenesulfonamide

There total 1 articles about N-[3-(tert-butyldimethylsilyl)-2-propynyl]-N-2-propenyl-p-toluenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

tert-butyldimethylsilyl chloride (18162-48-6) + N-tosyl-N-allylpropargylamine (133886-40-5) → N-[3-(tert-butyldimethylsilyl)-2-propynyl]-N-2-propenyl-p-toluenesulfonamide (1202400-45-0)

Guidance literature:

N-tosyl-N-allylpropargylamine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

tert-butyldimethylsilyl chloride; In tetrahydrofuran; hexane; at -78 - 20 ℃;

DOI:10.1021/ol902562j

Reference yield: 65.0%

N-[3-(tert-butyldimethylsilyl)-2-propynyl]-N-2-propenyl-p-toluenesulfonamide (1202400-45-0) → 3-[chloro(tert-butyldimethylsilyl)methylene]-4-methyl-1-tosylpyrrolidine (1202400-61-0)

Guidance literature:

With iron(III) chloride; sodium tetrahydroborate; air; In tetrahydrofuran; at 0 - 20 ℃; under 760.051 Torr;

DOI:10.1021/ol902562j

upstream raw materials:

tert-butyldimethylsilyl chloride

N-tosyl-N-allylpropargylamine

Downstream raw materials:

3-[chloro(tert-butyldimethylsilyl)methylene]-4-methyl-1-tosylpyrrolidine