Sermorelin

Base Information

• Chemical Name: Sermorelin
• CAS No.: 86168-78-7
• Molecular Formula: C149H246N44O42S
• Molecular Weight: 3357.88
• DSSTox Substance ID: DTXSID70903978
• NCI Thesaurus Code: C62088
• Wikipedia: Sermorelin
• Mol file: 86168-78-7.mol

Synonyms:Sermorelin [INN:BAN];Somatoliberin (human pancreatic islet), 29-L-argininamide-30-de-L-glutamine-31-de-L-glutamine-32-deglycine-33-de-L-glutamic acid-34-de-L-serine-35-de-L-asparagine-36-de-L-glutamine-37-de-L-glutamic acid-38-de-L-arginine-39-deglycine-40-de-L-alanine-41-de-L-arginine-42-de-L-alanine-43-de-L-argininyl-44-de-L-leucinamide;Sermorelina;Sermorelina [Spanish];Sermoreline;Sermoreline [French];Sermorelinum;Sermorelinum [Latin];UNII-89243S03TE;

Chemical Property of Sermorelin

Chemical Property:

• Appearance/Colour: White powder
• Refractive Index: 1.649
• PSA: 1472.20000
• Density: 1.45 g/cm³
• LogP: 5.07090
• Storage Temp.: −20°C
• Solubility.: Acetic Acid (Slightly), Trifluoroacetic Acid (Slightly), Water (Slightly)
• XLogP3: -12.1
• Hydrogen Bond Donor Count: 52
• Hydrogen Bond Acceptor Count: 49
• Rotatable Bond Count: 118
• Exact Mass: 3356.8220541
• Heavy Atom Count: 236
• Complexity: 7640

Purity/Quality:

98% ^*data from raw suppliers

Growth Hormone Releasing Factor Fragment 1-29 amide human ≥97% (HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)O)C(=O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C(C)CC)C(=O)NC(CCSC)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)N)NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(CC3=CC=C(C=C3)O)N
• Isomeric SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CC3=CC=C(C=C3)O)N
• Description: Sermorelin consists of 29 amino acid residues, corresponding to the amino-terminal segment of GHRH. It belongs to the category of growth hormone-releasing hormone analogs. Sermorelin acetate is a synthetic peptide corresponding to the amino-terminal segment of the human growth hormone-releasing hormone (GHRH or GRF). It is the acetate salt of an amidated synthetic 29-amino acid peptide.
• Uses and Mechanism of Action: Sermorelin is used for the diagnosis or treatment of patients with growth hormone deficiency. It is also utilized in bodybuilding to increase muscle mass and reduce body fat. Additionally, it can be used to stimulate hair growth and improve exercise performance. Sermorelin stimulates the pituitary gland to release growth hormone (GH) by mimicking the action of endogenous GHRH.