ethyl 2-ethoxy-4-methoxybenzimidate

Base Information

• Chemical Name: ethyl 2-ethoxy-4-methoxybenzimidate
• CAS No.: 814917-14-1
• Molecular Formula: C₁₂H₁₇NO₃
• Molecular Weight: 223.272
• Mol file: 814917-14-1.mol

Synonyms:ethyl 2-ethoxy-4-methoxybenzimidate

Chemical Property of ethyl 2-ethoxy-4-methoxybenzimidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of ethyl 2-ethoxy-4-methoxybenzimidate

There total 1 articles about ethyl 2-ethoxy-4-methoxybenzimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

2-ethoxy-4-methoxybenzonitrile (224789-17-7) + ethanol (64-17-5) → ethyl 2-ethoxy-4-methoxybenzimidate (814917-14-1)

Guidance literature:

With acetyl chloride; at 0 - 20 ℃;

DOI:10.1016/j.bmc.2012.11.026

Reference yield: 75.0%

ethyl 2-ethoxy-4-methoxybenzimidate (814917-14-1) + meso-1,2-bis(4-bromophenyl)-1,2-ethanediamine (117903-53-4) → 4,5-bis(4-bromophenyl)-2-(2-ethoxy-4-methoxyphenyl)-4,5-dihydroimidazole

Guidance literature:

With dmap; triethylamine; In ethanol; for 4h; Microwave irradiation; Sealed tube; Heating;

DOI:10.1016/j.bmc.2012.11.026

Reference yield:

ethyl 2-ethoxy-4-methoxybenzimidate (814917-14-1) → (4,5-bis(4-bromophenyl)-2-(2-ethoxy-4-methoxyphenyl)-4,5-dihydroimidazolyl)(4-(2-hydroxyethyl)piperazinyl)methanone

Guidance literature:

Multi-step reaction with 2 steps

1.1: triethylamine; dmap / ethanol / 4 h / Microwave irradiation; Sealed tube; Heating

2.1: triethylamine / dichloromethane; toluene / 1 h / 20 °C / Inert atmosphere

2.2: 0 - 20 °C

With dmap; triethylamine; In ethanol; dichloromethane; toluene;

DOI:10.1016/j.bmc.2012.11.026

upstream raw materials:

2-ethoxy-4-methoxybenzonitrile

ethanol