((E)-(R)-7,7-Dibromo-4-methyl-hepta-2,6-dienyloxymethyl)-benzene

Base Information

• Chemical Name: ((E)-(R)-7,7-Dibromo-4-methyl-hepta-2,6-dienyloxymethyl)-benzene
• CAS No.: 132096-78-7
• Molecular Formula: C₁₅H₁₈Br₂O
• Molecular Weight: 374.115
• Mol file: 132096-78-7.mol

Synonyms:((E)-(R)-7,7-Dibromo-4-methyl-hepta-2,6-dienyloxymethyl)-benzene

Chemical Property of ((E)-(R)-7,7-Dibromo-4-methyl-hepta-2,6-dienyloxymethyl)-benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ((E)-(R)-7,7-Dibromo-4-methyl-hepta-2,6-dienyloxymethyl)-benzene

There total 2 articles about ((E)-(R)-7,7-Dibromo-4-methyl-hepta-2,6-dienyloxymethyl)-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

carbon tetrabromide (558-13-4) + (E)-(R)-6-Benzyloxy-3-methyl-hex-4-enal (141207-18-3) → ((E)-(R)-7,7-Dibromo-4-methyl-hepta-2,6-dienyloxymethyl)-benzene (132096-78-7)

Guidance literature:

With triphenylphosphine; In dichloromethane; at 0 ℃;

DOI:10.3987/COM-91-S17

Reference yield:

(E)-(R)-6-Benzyloxy-3-methyl-hex-4-enoic acid ethyl ester (111149-41-8) → ((E)-(R)-7,7-Dibromo-4-methyl-hepta-2,6-dienyloxymethyl)-benzene (132096-78-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / diisobutylaluminum hydride / toluene / -90 °C

2: 88 percent / PPh₃ / CH₂Cl₂ / 0 °C

With diisobutylaluminium hydride; triphenylphosphine; In dichloromethane; toluene;

DOI:10.3987/COM-91-S17

Reference yield: 82.0%

((E)-(R)-7,7-Dibromo-4-methyl-hepta-2,6-dienyloxymethyl)-benzene (132096-78-7) → ((E)-(R)-4-Methyl-hept-2-en-6-ynyloxymethyl)-benzene (132096-79-8)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at -78 ℃;

DOI:10.3987/COM-91-S17

upstream raw materials:

carbon tetrabromide

(E)-(R)-6-Benzyloxy-3-methyl-hex-4-enal

(E)-(R)-6-Benzyloxy-3-methyl-hex-4-enoic acid ethyl ester

Downstream raw materials:

((E)-(R)-4-Methyl-hept-2-en-6-ynyloxymethyl)-benzene

(S)-2-((2E,6E)-(R)-8-Benzyloxy-3,5-dimethyl-octa-2,6-dienyl)-oxirane

(4E,8E)-(2R,7R)-10-Benzyloxy-1-chloro-5,7-dimethyl-deca-4,8-dien-2-ol

(6E,10E)-(4R,9R)-12-Benzyloxy-7,9-dimethyl-dodeca-6,10-dien-1-yn-4-ol