Technology Process of 2-(N-benzyloxycarbonyl)amino-2,3,5-trideoxy-L-threo-hexono-1,4-lactone
There total 9 articles about 2-(N-benzyloxycarbonyl)amino-2,3,5-trideoxy-L-threo-hexono-1,4-lactone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; methyl orange; sodium cyanoborohydride;
In
methanol;
at 20 ℃;
for 1h;
pH=3.1;
DOI:10.1021/jo990445+
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 89 percent / CuSO4; p-toluenesulfonic acid / 20 h / 20 °C
2: pyridine / 0 - 20 °C
3: 89 percent / sodium azide / dimethylformamide / 24 h / 20 °C
4: 85 percent / hydrogen / Pd/charcoal / ethyl acetate / 1 h / Heating
5: 0.70 g / NaHCO3 / ethyl acetate; H2O / 3 h
6: 94 percent / HCl / methanol; H2O / Heating
7: sodium periodate / methanol / 3 h
8: 87 mg / NaBH3CN; methyl orange; HCl / methanol / 1 h / 20 °C / pH 3.1
With
pyridine; hydrogenchloride; sodium periodate; sodium azide; hydrogen; methyl orange; sodium cyanoborohydride; sodium hydrogencarbonate; toluene-4-sulfonic acid; copper(II) sulfate;
palladium on activated charcoal;
In
methanol; water; ethyl acetate; N,N-dimethyl-formamide;
1: cyclohexylidenation / 2: Tosylation / 3: Substitution / 4: Hydrogenation / 5: Acylation / 6: Hydrolysis / 7: Oxidation / 8: Reduction;
DOI:10.1021/jo990445+
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 89 percent / sodium azide / dimethylformamide / 24 h / 20 °C
2: 85 percent / hydrogen / Pd/charcoal / ethyl acetate / 1 h / Heating
3: 0.70 g / NaHCO3 / ethyl acetate; H2O / 3 h
4: 94 percent / HCl / methanol; H2O / Heating
5: sodium periodate / methanol / 3 h
6: 87 mg / NaBH3CN; methyl orange; HCl / methanol / 1 h / 20 °C / pH 3.1
With
hydrogenchloride; sodium periodate; sodium azide; hydrogen; methyl orange; sodium cyanoborohydride; sodium hydrogencarbonate;
palladium on activated charcoal;
In
methanol; water; ethyl acetate; N,N-dimethyl-formamide;
1: Substitution / 2: Hydrogenation / 3: Acylation / 4: Hydrolysis / 5: Oxidation / 6: Reduction;
DOI:10.1021/jo990445+
