8-alpha-Hydroxyverrucarin A

Base Information

Chemical Name:8-alpha-Hydroxyverrucarin A
CAS No.:74516-62-4
Molecular Formula:C₂₇H₃₄O₁₀
Molecular Weight:518.561
Hs Code.:
NSC Number:318142,291312

Synonyms:alpha-Allylic alcohol of Verrucarin A;74516-62-4;8-Hydroxy verrucarin A;8-alpha-Hydroxyverrucarin A;NSC291312;Verrucarin A, 8-hydroxy-, (8S)-;NSC 318142;8-.alpha.-Hydroxyverrucarin A;VERRUCARIN A, 8-HYDROXY;8.ALPHA.-HYDROXYVERRUCARIN A;NSC318142;NSC-291312;NSC-318142;.alpha.-Allylic alcohol of Verrucarin A;VERRUCARIN A, A-ALLYLIC ALCOHOL OF

Suppliers and Price of 8-alpha-Hydroxyverrucarin A

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 8-alpha-Hydroxyverrucarin A

Chemical Property:

Boiling Point:790.3°Cat760mmHg
Flash Point:264.5°C
Density:1.37g/cm³
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:0
Exact Mass:518.21519728
Heavy Atom Count:37
Complexity:1060

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1CCOC(=O)C=CC=CC(=O)OC2CC3C4(C2(C5(CC(C(=CC5O3)C)O)COC(=O)C1O)C)CO4
Isomeric SMILES:CC1CCOC(=O)/C=C/C=C/C(=O)OC2CC3C4(C2(C5(CC(C(=CC5O3)C)O)COC(=O)C1O)C)CO4

Technology Process of 8-alpha-Hydroxyverrucarin A

There total 3 articles about 8-alpha-Hydroxyverrucarin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 74526-04-8
16-oxoverrucarin A

: 74516-68-0
8α-hydroxy-9,10-dihydroverrucarin A

: 74516-62-4,74608-63-2
8α-hydroxyverrucarin A

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; ethanol; at -35 ℃; for 1.5h;
DOI:10.1021/jm00183a018

Reference yield:

: 3148-09-2
verrucarin A

: 74516-62-4,74608-63-2
8α-hydroxyverrucarin A

Guidance literature:: Multi-step reaction with 3 steps

1: 8.1 percent / SeO₂, Ac₂O, AcOH / 0.75 h / 100 °C

2: 63 percent / CrO₃, pyridine / CH₂Cl₂ / 1 h / Ambient temperature

3: 62 percent / NaBH₄ / tetrahydrofuran; ethanol / 1.5 h / -35 °C

With pyridine; chromium(VI) oxide; sodium tetrahydroborate; selenium(IV) oxide; acetic anhydride; acetic acid; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1021/jm00183a018

Reference yield:

: 74516-64-6
16-hydroxyverrucarin A

: 74516-62-4,74608-63-2
8α-hydroxyverrucarin A

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / CrO₃, pyridine / CH₂Cl₂ / 1 h / Ambient temperature

2: 62 percent / NaBH₄ / tetrahydrofuran; ethanol / 1.5 h / -35 °C

With pyridine; chromium(VI) oxide; sodium tetrahydroborate; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1021/jm00183a018