3-benzyl-2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

Base Information

Chemical Name:3-benzyl-2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one
CAS No.:341007-56-5
Molecular Formula:C₂₁H₁₇ClN₂O
Molecular Weight:348.832
Hs Code.:
Mol file:341007-56-5.mol

Synonyms:3-benzyl-2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

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Chemical Property of 3-benzyl-2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

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Technology Process of 3-benzyl-2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

There total 6 articles about 3-benzyl-2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 118-48-9
isatoic anhydride

: 104-88-1
4-chlorobenzaldehyde

: 100-46-9
benzylamine

: 341007-56-5
3-benzyl-2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: With copper-((1H-benzo[d]imidazol-2-yl)methanamine) complex supported on silica-coated magnetic cobalt ferrite nanoparticles; In water; for 0.5h; Reflux;
DOI:10.1080/00958972.2021.1905803

Reference yield:

: 104-88-1
4-chlorobenzaldehyde

: 5471-20-5
2-amino-N-benzylbenzamide

: 341007-56-5
3-benzyl-2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: With iodine; potassium carbonate; In water; for 3h; Reflux; Green chemistry;
DOI:10.1016/j.tetlet.2015.11.090

Reference yield:

: 873-76-7
para-Chlorobenzyl alcohol

: 341007-56-5
3-benzyl-2-(4-chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: iodine; potassium carbonate / water / 3 h / Reflux; Green chemistry

2: iodine; potassium carbonate / water / 3 h / Reflux; Green chemistry

With iodine; potassium carbonate; In water;
DOI:10.1016/j.tetlet.2015.11.090