(7R,8R)-7-Nitro-8-((R)-2-oxo-4-phenyl-oxazolidin-3-yl)-nonanoic acid methyl ester

Base Information

Chemical Name:(7R,8R)-7-Nitro-8-((R)-2-oxo-4-phenyl-oxazolidin-3-yl)-nonanoic acid methyl ester
CAS No.:316807-08-6
Molecular Formula:C₁₉H₂₆N₂O₆
Molecular Weight:378.425
Hs Code.:

Synonyms:(7R,8R)-7-Nitro-8-((R)-2-oxo-4-phenyl-oxazolidin-3-yl)-nonanoic acid methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (7R,8R)-7-Nitro-8-((R)-2-oxo-4-phenyl-oxazolidin-3-yl)-nonanoic acid methyl ester

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Technology Process of (7R,8R)-7-Nitro-8-((R)-2-oxo-4-phenyl-oxazolidin-3-yl)-nonanoic acid methyl ester

There total 1 articles about (7R,8R)-7-Nitro-8-((R)-2-oxo-4-phenyl-oxazolidin-3-yl)-nonanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 90319-52-1,7480-32-2
(4R)-phenyl-2-oxazolidinone

: methyl 7-nitronon-7-enoate

: 316807-07-5
(7S,8R)-7-Nitro-8-((R)-2-oxo-4-phenyl-oxazolidin-3-yl)-nonanoic acid methyl ester

: 316807-08-6
(7R,8R)-7-Nitro-8-((R)-2-oxo-4-phenyl-oxazolidin-3-yl)-nonanoic acid methyl ester

Guidance literature:: With 18-crown-6 ether; potassium tert-butylate; In tetrahydrofuran; at -78 ℃; for 0.75h;
DOI:10.1002/1099-0690(200011)2000:21<3575::aid-ejoc3575>3.0.co;2-r

Reference yield: 72.0%

: 316807-08-6
(7R,8R)-7-Nitro-8-((R)-2-oxo-4-phenyl-oxazolidin-3-yl)-nonanoic acid methyl ester

: 316807-12-2
(7R,8R)-7-Amino-8-((R)-2-oxo-4-phenyl-oxazolidin-3-yl)-nonanoic acid methyl ester

Guidance literature:: With ammonium formate; palladium on activated charcoal; In methanol; at 20 ℃; for 72h;
DOI:10.1002/1099-0690(200011)2000:21<3575::aid-ejoc3575>3.0.co;2-r

Reference yield:

: 316807-08-6
(7R,8R)-7-Nitro-8-((R)-2-oxo-4-phenyl-oxazolidin-3-yl)-nonanoic acid methyl ester

: 316807-13-3
6-[(4R,5R)-1-((R)-2-Hydroxy-1-phenyl-ethyl)-5-methyl-2-oxo-imidazolidin-4-yl]-hexanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / ammonium formate / Pd/C / methanol / 72 h / 20 °C

2: 89 percent / KOH; water / methanol / 16 h / Heating

With potassium hydroxide; water; ammonium formate; palladium on activated charcoal; In methanol; 1: Reduction / 2: Hydrolysis;
DOI:10.1002/1099-0690(200011)2000:21<3575::aid-ejoc3575>3.0.co;2-r