Technology Process of 2-(5-tert-butyl-2-ethyl-1H-inden-7-yl)-1,1,2,2-tetramethyl-N-(2-methylphenyl)disilanamine
There total 8 articles about 2-(5-tert-butyl-2-ethyl-1H-inden-7-yl)-1,1,2,2-tetramethyl-N-(2-methylphenyl)disilanamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
o-toluidine;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at 20 ℃;
for 3h;
1,2-dichlorotetramethylsilane; 7-bromo-5-tert-butyl-2-ethyl-1H-indene;
With
magnesium; ethylene dibromide;
In
tetrahydrofuran; hexane;
Overall yield = 61 %; Overall yield = 5.04 g;
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: iodine; bromine / water / 14 h / 5 - 20 °C
2.1: bromine; dibenzoyl peroxide / tetrachloromethane / Reflux
3.1: sodium ethanolate / 5 h / 20 °C / Reflux
4.1: sodium ethanolate / 4 h / Reflux
4.2: 5 h / Reflux
5.1: thionyl chloride / 12 h / 20 °C
6.1: aluminum (III) chloride / dichloromethane / 0 - 20 °C
7.1: sodium tetrahydroborate; methanol / tetrahydrofuran / 5 h / 5 °C
7.2: pH 5
7.3: 1 h / Reflux
8.1: n-butyllithium / tetrahydrofuran; hexane / 3 h / 20 °C
With
methanol; aluminum (III) chloride; sodium tetrahydroborate; n-butyllithium; thionyl chloride; bromine; iodine; sodium ethanolate; dibenzoyl peroxide;
In
tetrahydrofuran; tetrachloromethane; hexane; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: bromine; dibenzoyl peroxide / tetrachloromethane / Reflux
2.1: sodium ethanolate / 5 h / 20 °C / Reflux
3.1: sodium ethanolate / 4 h / Reflux
3.2: 5 h / Reflux
4.1: thionyl chloride / 12 h / 20 °C
5.1: aluminum (III) chloride / dichloromethane / 0 - 20 °C
6.1: sodium tetrahydroborate; methanol / tetrahydrofuran / 5 h / 5 °C
6.2: pH 5
6.3: 1 h / Reflux
7.1: n-butyllithium / tetrahydrofuran; hexane / 3 h / 20 °C
With
methanol; aluminum (III) chloride; sodium tetrahydroborate; n-butyllithium; thionyl chloride; bromine; sodium ethanolate; dibenzoyl peroxide;
In
tetrahydrofuran; tetrachloromethane; hexane; dichloromethane;
