4-Furfurylamino-7-(beta-D-ribofuranosyl)pyrrolo(2,3-d)-pyrimidine

Base Information

Chemical Name:4-Furfurylamino-7-(beta-D-ribofuranosyl)pyrrolo(2,3-d)-pyrimidine
CAS No.:52017-19-3
Molecular Formula:C16H18N4O5
Molecular Weight:346.3379
Hs Code.:
DSSTox Substance ID:DTXSID00199988
Wikidata:Q83073006

Synonyms:4-furfurylamino-7-(beta-D-ribofuranosyl)pyrrolo(2,3-d)-pyrimidine

Suppliers and Price of 4-Furfurylamino-7-(beta-D-ribofuranosyl)pyrrolo(2,3-d)-pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-Furfurylamino-7-(beta-D-ribofuranosyl)pyrrolo(2,3-d)-pyrimidine

Chemical Property:

Vapor Pressure:1.29E-18mmHg at 25°C
Boiling Point:665.4°Cat760mmHg
Flash Point:356.2°C
Density:1.68g/cm³
XLogP3:-0.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:346.12771969
Heavy Atom Count:25
Complexity:458

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=COC(=C1)CNC2=C3C=CN(C3=NC=N2)C4C(C(C(O4)CO)O)O
Isomeric SMILES:C1=COC(=C1)CNC2=C3C=CN(C3=NC=N2)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O

Technology Process of 4-Furfurylamino-7-(beta-D-ribofuranosyl)pyrrolo(2,3-d)-pyrimidine

There total 2 articles about 4-Furfurylamino-7-(beta-D-ribofuranosyl)pyrrolo(2,3-d)-pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98-00-0,25212-86-6,93793-62-5
(2-furyl)methyl alcohol

: 4-acetylamino-7-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

: 52017-19-3
4-furfurylamino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: (2-furyl)methyl alcohol; 4-acetylamino-7-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene; at 20 ℃;

With ammonium hydroxide; In methanol; dichloromethane; at 20 ℃;
DOI:10.1016/j.molstruc.2019.05.112

Reference yield:

: 69-33-0
tubercidin

: 52017-19-3
4-furfurylamino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1.1: pyridine / 20 - 60 °C

1.2: 8 h / 20 °C

2.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran; toluene / 20 °C

2.2: 20 °C

With pyridine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene; 2.1: |Mitsunobu Displacement;
DOI:10.1016/j.molstruc.2019.05.112