2-[(2-benzyl-2-({2-({2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl}amino)-1-oxopropyl)amino]-2,N,N-trimethylpropanamide

Base Information

• Chemical Name: 2-[(2-benzyl-2-({2-({2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl}amino)-1-oxopropyl)amino]-2,N,N-trimethylpropanamide
• CAS No.: 339315-35-4
• Molecular Formula: C₂₉H₄₇N₅O₆
• Molecular Weight: 561.722
• Mol file: 339315-35-4.mol

Synonyms:2-[(2-benzyl-2-({2-({2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl}amino)-1-oxopropyl)amino]-2,N,N-trimethylpropanamide

Chemical Property of 2-[(2-benzyl-2-({2-({2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl}amino)-1-oxopropyl)amino]-2,N,N-trimethylpropanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[(2-benzyl-2-({2-({2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl}amino)-1-oxopropyl)amino]-2,N,N-trimethylpropanamide

There total 7 articles about 2-[(2-benzyl-2-({2-({2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl}amino)-1-oxopropyl)amino]-2,N,N-trimethylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

3-dimethylamino-2,2-dimethyl-2H-azirine (54856-83-6) + 2-benzyl-2-{[-({2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}propanoic acid (339315-30-9) → 2-[(2-benzyl-2-({2-({2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl}amino)-1-oxopropyl)amino]-2,N,N-trimethylpropanamide (339315-35-4)

Guidance literature:

In acetonitrile; at 20 ℃; for 21h;

DOI:10.1016/S0040-4020(01)00091-6

Reference yield:

3-Hydroxy-2,2-dimethylpropanoic acid (4835-90-9) → 2-[(2-benzyl-2-({2-({2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl}amino)-1-oxopropyl)amino]-2,N,N-trimethylpropanamide (339315-35-4)

Guidance literature:

Multi-step reaction with 7 steps

1: 93 percent / acetonitrile / 17 h / 20 °C

2: 36 percent / 3N HCl / tetrahydrofuran / 23 h / 20 °C

3: 90 percent / acetonitrile / 19 h / 20 °C

4: aq. HCl / tetrahydrofuran / 23 h / 20 °C

5: 0.297 g / acetonitrile / 23 h / 20 °C

6: 83 percent / aq. HCl / tetrahydrofuran / 18 h / 20 °C

7: 77 percent / acetonitrile / 21 h / 20 °C

With hydrogenchloride; In tetrahydrofuran; acetonitrile;

DOI:10.1016/S0040-4020(01)00091-6

Reference yield:

2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-2-methylpropanoic acid (339315-18-3) → 2-[(2-benzyl-2-({2-({2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl}amino)-1-oxopropyl)amino]-2,N,N-trimethylpropanamide (339315-35-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 90 percent / acetonitrile / 19 h / 20 °C

2: aq. HCl / tetrahydrofuran / 23 h / 20 °C

3: 0.297 g / acetonitrile / 23 h / 20 °C

4: 83 percent / aq. HCl / tetrahydrofuran / 18 h / 20 °C

5: 77 percent / acetonitrile / 21 h / 20 °C

With hydrogenchloride; In tetrahydrofuran; acetonitrile;

DOI:10.1016/S0040-4020(01)00091-6

upstream raw materials:

3-dimethylamino-2,2-dimethyl-2H-azirine

2-benzyl-2-{[-({2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-2-methyl-1-oxopropyl}amino)-2-methyl-1-oxopropyl]amino}propanoic acid

3-Hydroxy-2,2-dimethylpropanoic acid

2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)amino]-2-methylpropanoic acid