{6-[2-methyl-5-(3-trifluoromethylbenzoylamino)phenylcarbamoyl]benzothiazol-2-yl}carbamic acid methyl ester

Base Information

Chemical Name:{6-[2-methyl-5-(3-trifluoromethylbenzoylamino)phenylcarbamoyl]benzothiazol-2-yl}carbamic acid methyl ester
CAS No.:1024583-49-0
Molecular Formula:C₂₅H₁₉F₃N₄O₄S
Molecular Weight:528.511
Hs Code.:

Synonyms:{6-[2-methyl-5-(3-trifluoromethylbenzoylamino)phenylcarbamoyl]benzothiazol-2-yl}carbamic acid methyl ester

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Chemical Property of {6-[2-methyl-5-(3-trifluoromethylbenzoylamino)phenylcarbamoyl]benzothiazol-2-yl}carbamic acid methyl ester

Chemical Property:

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Technology Process of {6-[2-methyl-5-(3-trifluoromethylbenzoylamino)phenylcarbamoyl]benzothiazol-2-yl}carbamic acid methyl ester

There total 3 articles about {6-[2-methyl-5-(3-trifluoromethylbenzoylamino)phenylcarbamoyl]benzothiazol-2-yl}carbamic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1024583-32-1
2-amino-benzothiazole-6-carboxylic acid [2-methyl-5-(3-trifluoromethyl-benzoylamino)-phenyl]-amide

: 79-22-1
methyl chloroformate

: 1024583-49-0
{6-[2-methyl-5-(3-trifluoromethylbenzoylamino)phenylcarbamoyl]benzothiazol-2-yl}carbamic acid methyl ester

Guidance literature:: DOI:10.1016/j.bmcl.2008.02.079

Reference yield:

: 30069-31-9
N-(3-amino-4-methylphenyl)-3-(trifluoromethyl)benzamide

: 1024583-49-0
{6-[2-methyl-5-(3-trifluoromethylbenzoylamino)phenylcarbamoyl]benzothiazol-2-yl}carbamic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C

2: trifluoroacetic acid / 0.5 h / 20 °C

3: tetrahydrofuran / 20 °C

With N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; In tetrahydrofuran; N,N-dimethyl-formamide;

Reference yield:

: 1024583-31-0
{6-[2-methyl-5-(3-trifluoromethyl-benzoylamino)-phenylcarbamoyl]-benzothiazol-2-yl}-carbamic acid tert-butyl ester

: 1024583-49-0
{6-[2-methyl-5-(3-trifluoromethylbenzoylamino)phenylcarbamoyl]benzothiazol-2-yl}carbamic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / 0.5 h / 20 °C

2: tetrahydrofuran / 20 °C

With trifluoroacetic acid; In tetrahydrofuran;