2-[3,5-bis(methoxymethoxy)-4-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

Chemical Name:2-[3,5-bis(methoxymethoxy)-4-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.:253604-39-6
Molecular Formula:C₁₇H₂₇BO₆
Molecular Weight:338.209
Hs Code.:

Synonyms:2-[3,5-bis(methoxymethoxy)-4-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Suppliers and Price of 2-[3,5-bis(methoxymethoxy)-4-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[3,5-bis(methoxymethoxy)-4-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[3,5-bis(methoxymethoxy)-4-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 5 articles about 2-[3,5-bis(methoxymethoxy)-4-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 121-43-7,63156-11-6
Trimethyl borate

: 253604-38-5
5-bromo-1,3-bis(methoxymethoxy)-2-methylbenzene

: 253604-39-6
2-[3,5-bis(methoxymethoxy)-4-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: Trimethyl borate; 5-bromo-1,3-bis(methoxymethoxy)-2-methylbenzene; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 4.5h;

With 2,3-dimethyl-2,3-butane diol; In benzene; for 12h; Heating;
DOI:10.1002/1522-2675(200202)85:2<571::AID-HLCA571>3.0.CO;2-Y

Reference yield: 96.0%

: 76-09-5
2,3-dimethyl-2,3-butane diol

: 253604-38-5
5-bromo-1,3-bis(methoxymethoxy)-2-methylbenzene

: 253604-39-6
2-[3,5-bis(methoxymethoxy)-4-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: 5-bromo-1,3-bis(methoxymethoxy)-2-methylbenzene; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; at -78 ℃; for 1h;

With Trimethyl borate; In tetrahydrofuran; at 20 ℃; for 2h;

2,3-dimethyl-2,3-butane diol; In benzene; for 12h; Heating;
DOI:10.1002/(SICI)1521-3773(19991102)38:21<3215::AID-ANIE3215>3.0.CO;2-S

Reference yield:

: 90561-18-5
5-bromo-1,3-dimethoxy-2-methylbenzene

: 253604-39-6
2-[3,5-bis(methoxymethoxy)-4-methylphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: Multi-step reaction with 3 steps

1.1: 94 percent / 56 percent aq. HI / acetic acid / 6 h / Heating

2.1: 96 percent / K₂CO₃ / acetonitrile / 0 - 20 °C

3.1: TMEDA; BuLi / tetrahydrofuran; hexane / 4.5 h / -78 - 20 °C

3.2: 97 percent / pinacol / benzene / 12 h / Heating

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; hydrogen iodide; potassium carbonate; In tetrahydrofuran; hexane; acetic acid; acetonitrile;
DOI:10.1002/1522-2675(200202)85:2<571::AID-HLCA571>3.0.CO;2-Y